Found: 27

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  • COSMIC: exploring the world's knowledge of somatic mutations in human cancer.

    Published in:
    Nucleic Acids Research, 2015, v. 43, n. D1, p. D805, doi. 10.1093/nar/gku1075
    By:
    • Forbes, Simon A.;
    • Beare, David;
    • Gunasekaran, Prasad;
    • Leung, Kenric;
    • Bindal, Nidhi;
    • Boutselakis, Harry;
    • Ding, Minjie;
    • Bamford, Sally;
    • Cole, Charlotte;
    • Ward, Sari;
    • Kok, Chai Yin;
    • Jia, Mingming;
    • De, Tisham;
    • Teague, Jon W.;
    • Stratton, Michael R.;
    • McDermott, Ultan;
    • Campbell, Peter J.
    Publication type:
    Article

  • Single-cell paired-end genome sequencing reveals structural variation per cell cycle.

    Published in:
    Nucleic Acids Research, 2013, v. 41, n. 12, p. 6119, doi. 10.1093/nar/gkt345
    By:
    • Voet, Thierry;
    • Kumar, Parveen;
    • Van Loo, Peter;
    • Cooke, Susanna L.;
    • Marshall, John;
    • Lin, Meng-Lay;
    • Zamani Esteki, Masoud;
    • Van der Aa, Niels;
    • Mateiu, Ligia;
    • McBride, David J.;
    • Bignell, Graham R.;
    • McLaren, Stuart;
    • Teague, Jon;
    • Butler, Adam;
    • Raine, Keiran;
    • Stebbings, Lucy A.;
    • Quail, Michael A.;
    • D’Hooghe, Thomas;
    • Moreau, Yves;
    • Futreal, P. Andrew
    Publication type:
    Article

  • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer.

    Published in:
    Nucleic Acids Research, 2011, v. 39, n. suppl_1, p. D945, doi. 10.1093/nar/gkq929
    By:
    • Forbes, Simon A.;
    • Bindal, Nidhi;
    • Bamford, Sally;
    • Cole, Charlotte;
    • Kok, Chai Yin;
    • Beare, David;
    • Jia, Mingming;
    • Shepherd, Rebecca;
    • Leung, Kenric;
    • Menzies, Andrew;
    • Teague, Jon W.;
    • Campbell, Peter J.;
    • Stratton, Michael R.;
    • Futreal, P. Andrew
    Publication type:
    Article

  • COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer.

    Published in:
    Nucleic Acids Research, 2010, v. 38, p. D652, doi. 10.1093/nar/gkp995
    By:
    • Forbes, Simon A.;
    • Tang, Gurpreet;
    • Bindal, Nidhi;
    • Bamford, Sally;
    • Dawson, Elisabeth;
    • Cole, Charlotte;
    • Chai Yin Kok;
    • Mingming Jia;
    • Ewing, Rebecca;
    • Menzies, Andrew;
    • Teague, Jon W.;
    • Stratton, Michael R.;
    • Futreal, P. Andrew
    Publication type:
    Article

  • Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes.

    Published in:
    Journal of Pathology, 2012, v. 227, n. 4, p. 446, doi. 10.1002/path.4042
    By:
    • McBride, David J;
    • Etemadmoghadam, Dariush;
    • Cooke, Susanna L;
    • Alsop, Kathryn;
    • George, Joshy;
    • Butler, Adam;
    • Cho, Juok;
    • Galappaththige, Danushka;
    • Greenman, Chris;
    • Howarth, Karen D;
    • Lau, King W;
    • Ng, Charlotte K;
    • Raine, Keiran;
    • Teague, Jon;
    • Wedge, David C;
    • Cancer Study Group, Australian Ovarian;
    • Caubit, Xavier;
    • Stratton, Michael R;
    • Brenton, James D;
    • Campbell, Peter J
    Publication type:
    Article

  • Recurrent PTPRB and PLCG1 mutations in angiosarcoma.

    Published in:
    Nature Genetics, 2014, v. 46, n. 4, p. 376, doi. 10.1038/ng.2921
    By:
    • Behjati, Sam;
    • Tarpey, Patrick S;
    • Sheldon, Helen;
    • Martincorena, Inigo;
    • Van Loo, Peter;
    • Gundem, Gunes;
    • Wedge, David C;
    • Ramakrishna, Manasa;
    • Cooke, Susanna L;
    • Pillay, Nischalan;
    • Vollan, Hans Kristian M;
    • Papaemmanuil, Elli;
    • Koss, Hans;
    • Bunney, Tom D;
    • Hardy, Claire;
    • Joseph, Olivia R;
    • Martin, Sancha;
    • Mudie, Laura;
    • Butler, Adam;
    • Teague, Jon W
    Publication type:
    Article

  • Corrigendum: Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.

    Published in:
    Nature Genetics, 2014, v. 46, n. 3, p. 316, doi. 10.1038/ng0314-316
    By:
    • Behjati, Sam;
    • Tarpey, Patrick S;
    • Presneau, Nadège;
    • Scheipl, Susanne;
    • Pillay, Nischalan;
    • Van Loo, Peter;
    • Wedge, David C;
    • Cooke, Susanna L;
    • Gundem, Gunes;
    • Davies, Helen;
    • Nik-Zainal, Serena;
    • Martin, Sancha;
    • McLaren, Stuart;
    • Goodie, Victoria;
    • Robinson, Ben;
    • Butler, Adam;
    • Teague, Jon W;
    • Halai, Dina;
    • Khatri, Bhavisha;
    • Myklebost, Ola
    Publication type:
    Article

  • Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.

    Published in:
    Nature Genetics, 2013, v. 45, n. 12, p. 1479, doi. 10.1038/ng.2814
    By:
    • Behjati, Sam;
    • Tarpey, Patrick S;
    • Presneau, Nadège;
    • Scheipl, Susanne;
    • Pillay, Nischalan;
    • Van Loo, Peter;
    • Wedge, David C;
    • Cooke, Susanna L;
    • Gundem, Gunes;
    • Davies, Helen;
    • Nik-Zainal, Serena;
    • Martin, Sancha;
    • McLaren, Stuart;
    • Goodie, Victoria;
    • Robinson, Ben;
    • Butler, Adam;
    • Teague, Jon W;
    • Halai, Dina;
    • Khatri, Bhavisha;
    • Myklebost, Ola
    Publication type:
    Article

  • Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.

    Published in:
    Nature Genetics, 2009, v. 41, n. 5, p. 521, doi. 10.1038/ng.349
    By:
    • van Haaften, Gijs;
    • Dalgliesh, Gillian L.;
    • Davies, Helen;
    • Chen, Lina;
    • Bignell, Graham;
    • Greenman, Chris;
    • Edkins, Sarah;
    • Hardy, Claire;
    • O'Meara, Sarah;
    • Teague, Jon;
    • Butler, Adam;
    • Hinton, Jonathan;
    • Latimer, Calli;
    • Andrews, Jenny;
    • Barthorpe, Syd;
    • Beare, Dave;
    • Buck, Gemma;
    • Campbell, Peter J.;
    • Cole, Jennifer;
    • Forbes, Simon
    Publication type:
    Article

  • Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.

    Published in:
    Nature Genetics, 2008, v. 40, n. 6, p. 722, doi. 10.1038/ng.128
    By:
    • Campbell, Peter J.;
    • Stephens, Philip J.;
    • Pleasance, Erin D.;
    • O'Meara, Sarah;
    • Heng Li;
    • Santarius, Thomas;
    • Stebbings, Lucy A.;
    • Leroy, Catherine;
    • Edkins, Sarah;
    • Hardy, Claire;
    • Teague, Jon W.;
    • Menzies, Andrew;
    • Goodhead, Ian;
    • Turner, Daniel J.;
    • Clee, Christopher M.;
    • Quail, Michael A.;
    • Cox, Antony;
    • Brown, Clive;
    • Durbin, Richard;
    • Hurles, Matthew E.
    Publication type:
    Article

  • A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.

    Published in:
    Nature Genetics, 2005, v. 37, n. 6, p. 590, doi. 10.1038/ng1571
    By:
    • Stephens, Philip;
    • Edkins, Sarah;
    • Davies, Helen;
    • Greenman, Chris;
    • Cox, Charles;
    • Hunter, Chris;
    • Bignell, Graham;
    • Teague, Jon;
    • Smith, Raffaella;
    • Stevens, Claire;
    • O'Meara, Sarah;
    • Parker, Adrian;
    • Tarpey, Patrick;
    • Avis, Tim;
    • Barthorpe, Andy;
    • Brackenbury, Lisa;
    • Buck, Gemma;
    • Butler, Adam;
    • Clements, Jody;
    • Cole, Jennifer
    Publication type:
    Article

  • Data mining using the Catalogue of Somatic Mutations in Cancer BioMart.

    Published in:
    Database: The Journal of Biological Databases & Curation, 2011, v. 2011, n. 18, p. 1
    By:
    • Shepherd, Rebecca;
    • Forbes, Simon A.;
    • Beare, David;
    • Bamford, S.;
    • Cole, Charlotte G.;
    • Ward, Sari;
    • Bindal, Nidhi;
    • Gunasekaran, Prasad;
    • Jia, Mingming;
    • Kok, Chai Yin;
    • Leung, Kenric;
    • Menzies, Andrew;
    • Butler, Adam P.;
    • Teague, Jon W.;
    • Campbell, Peter J.;
    • Stratton, Michael R.;
    • Futreal, P. Andrew
    Publication type:
    Article

  • Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

    Published in:
    Nature, 2011, v. 469, n. 7331, p. 539, doi. 10.1038/nature09639
    By:
    • Varela, Ignacio;
    • Tarpey, Patrick;
    • Raine, Keiran;
    • Huang, Dachuan;
    • Ong, Choon Kiat;
    • Stephens, Philip;
    • Davies, Helen;
    • Jones, David;
    • Meng-Lay Lin;
    • Teague, Jon;
    • Bignell, Graham;
    • Butler, Adam;
    • Cho, Juok;
    • Dalgliesh, Gillian L.;
    • Galappaththige, Danushka;
    • Greenman, Chris;
    • Hardy, Claire;
    • Mingming Jia;
    • Latimer, Calli;
    • King Wai Lau
    Publication type:
    Article

  • The patterns and dynamics of genomic instability in metastatic pancreatic cancer.

    Published in:
    Nature, 2010, v. 467, n. 7319, p. 1109, doi. 10.1038/nature09460
    By:
    • Campbell, Peter J.;
    • Yachida, Shinichi;
    • Mudie, Laura J.;
    • Stephens, Philip J.;
    • Pleasance, Erin D.;
    • Stebbings, Lucy A.;
    • Morsberger, Laura A.;
    • Latimer, Calli;
    • McLaren, Stuart;
    • Lin, Meng-Lay;
    • McBride, David J.;
    • Varela, Ignacio;
    • Nik-Zainal, Serena A.;
    • Leroy, Catherine;
    • Jia, Mingming;
    • Menzies, Andrew;
    • Butler, Adam P.;
    • Teague, Jon W.;
    • Griffin, Constance A.;
    • Burton, John
    Publication type:
    Article

  • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.

    Published in:
    Nature, 2010, v. 463, n. 7279, p. 360, doi. 10.1038/nature08672
    By:
    • Dalgliesh, Gillian L.;
    • Furge, Kyle;
    • Greenman, Chris;
    • Chen, Lina;
    • Bignell, Graham;
    • Butler, Adam;
    • Davies, Helen;
    • Edkins, Sarah;
    • Hardy, Claire;
    • Latimer, Calli;
    • Teague, Jon;
    • Andrews, Jenny;
    • Barthorpe, Syd;
    • Beare, Dave;
    • Buck, Gemma;
    • Campbell, Peter J.;
    • Forbes, Simon;
    • Mingming Jia;
    • Jones, David;
    • Knott, Henry
    Publication type:
    Article

  • Complex landscapes of somatic rearrangement in human breast cancer genomes.

    Published in:
    Nature, 2009, v. 462, n. 7276, p. 1005, doi. 10.1038/nature08645
    By:
    • Stephens, Philip J.;
    • McBride, David J.;
    • Meng-Lay Lin;
    • Varela, Ignacio;
    • Pleasance, Erin D.;
    • Simpson, Jared T.;
    • Stebbings, Lucy A.;
    • Leroy, Catherine;
    • Edkins, Sarah;
    • Mudie, Laura J.;
    • Greenman, Chris D.;
    • Mingming Jia;
    • Latimer, Calli;
    • Teague, Jon W.;
    • King Wai Lau;
    • Burton, John;
    • Quail, Michael A.;
    • Swerdlow, Harold;
    • Churcher, Carol;
    • Natrajan, Rachael
    Publication type:
    Article

  • Patterns of somatic mutation in human cancer genomes.

    Published in:
    Nature, 2007, v. 446, n. 7132, p. 153, doi. 10.1038/nature05610
    By:
    • Greenman, Christopher;
    • Stephens, Philip;
    • Smith, Raffaella;
    • Dalgliesh, Gillian L.;
    • Hunter, Christopher;
    • Bignell, Graham;
    • Davies, Helen;
    • Teague, Jon;
    • Butler, Adam;
    • Stevens, Claire;
    • Edkins, Sarah;
    • O’Meara, Sarah;
    • Vastrik, Imre;
    • Schmidt, Esther E.;
    • Avis, Tim;
    • Barthorpe, Syd;
    • Bhamra, Gurpreet;
    • Buck, Gemma;
    • Choudhury, Bhudipa;
    • Clements, Jody
    Publication type:
    Article

  • Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.

    Published in:
    Nature Communications, 2017, v. 8, n. 6, p. 15936, doi. 10.1038/ncomms15936
    By:
    • Behjati, Sam;
    • Tarpey, Patrick S.;
    • Haase, Kerstin;
    • Ye, Hongtao;
    • Young, Matthew D.;
    • Alexandrov, Ludmil B.;
    • Farndon, Sarah J.;
    • Collord, Grace;
    • Wedge, David C.;
    • Martincorena, Inigo;
    • Cooke, Susanna L.;
    • Davies, Helen;
    • Mifsud, William;
    • Lidgren, Mathias;
    • Martin, Sancha;
    • Latimer, Calli;
    • Maddison, Mark;
    • Butler, Adam P.;
    • Teague, Jon W.;
    • Pillay, Nischalan
    Publication type:
    Article

  • Mutational signatures of ionizing radiation in second malignancies.

    Published in:
    Nature Communications, 2016, v. 7, n. 9, p. 12605, doi. 10.1038/ncomms12605
    By:
    • Behjati, Sam;
    • Gundem, Gunes;
    • Wedge, David C.;
    • Roberts, Nicola D.;
    • Tarpey, Patrick S.;
    • Cooke, Susanna L.;
    • Van Loo, Peter;
    • Alexandrov, Ludmil B.;
    • Ramakrishna, Manasa;
    • Davies, Helen;
    • Nik-Zainal, Serena;
    • Hardy, Claire;
    • Latimer, Calli;
    • Raine, Keiran M.;
    • Stebbings, Lucy;
    • Menzies, Andy;
    • Jones, David;
    • Shepherd, Rebecca;
    • Butler, Adam P.;
    • Teague, Jon W.
    Publication type:
    Article

  • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.

    Published in:
    Nature Communications, 2014, v. 5, n. 1, p. 2997, doi. 10.1038/ncomms3997
    By:
    • Bolli, Niccolo;
    • Avet-Loiseau, Hervé;
    • Wedge, David C.;
    • Van Loo, Peter;
    • Alexandrov, Ludmil B.;
    • Martincorena, Inigo;
    • Dawson, Kevin J.;
    • Iorio, Francesco;
    • Nik-Zainal, Serena;
    • Bignell, Graham R.;
    • Hinton, Jonathan W.;
    • Li, Yilong;
    • Tubio, Jose M.C.;
    • McLaren, Stuart;
    • O' Meara, Sarah;
    • Butler, Adam P.;
    • Teague, Jon W.;
    • Mudie, Laura;
    • Anderson, Elizabeth;
    • Rashid, Naim
    Publication type:
    Article

  • Polygenic in vivo validation of cancer mutations using transposons.

    Published in:
    Genome Biology, 2014, v. 15, n. 9, p. 1, doi. 10.1186/s13059-014-0455-6
    By:
    • Su Chew;
    • Dong Lu;
    • Lia Campos;
    • Kenneth Scott;
    • Abdel Saci;
    • Juexuan Wang;
    • Adam Collinson;
    • Keiran Raine;
    • Jonathan Hinton;
    • Jon Teague;
    • David Jones;
    • Andrew Menzies;
    • Adam Butler;
    • John Gamble;
    • Sarah O'Meara;
    • Stuart McLaren;
    • Lynda Chin;
    • Pentao Liu;
    • Andrew Futreal, P.
    Publication type:
    Article

  • Lung cancer: Intragenic ERBB2 kinase mutations in tumours.

    Published in:
    Nature, 2004, v. 431, n. 7008, p. 525, doi. 10.1038/431525b
    By:
    • Stephens, Philip;
    • Hunter, Chris;
    • Bignell, Graham;
    • Edkins, Sarah;
    • Davies, Helen;
    • Teague, Jon;
    • Stevens, Claire;
    • O'Meara, Sarah;
    • Smith, Raffaella;
    • Parker, Adrian;
    • Barthorpe, Andy;
    • Blow, Matthew;
    • Brackenbury, Lisa;
    • Butler, Adam;
    • Clarke, Oliver;
    • Cole, Jennifer;
    • Dicks, Ed;
    • Dike, Angus;
    • Drozd, Anja;
    • Edwards, Ken
    Publication type:
    Article

  • Mutations of the BRAF gene in human cancer.

    Published in:
    Nature, 2002, v. 417, n. 6892, p. 949, doi. 10.1038/nature00766
    By:
    • Davies, Helen;
    • Bignell, Graham R.;
    • Cox, Charles;
    • Stephens, Philip;
    • Edkins, Sarah;
    • Clegg, Sheila;
    • Teague, Jon;
    • Woffendin, Hayley;
    • Garnett, Mathew J.;
    • Bottomley, William;
    • Davis, Neil;
    • Dicks, Ed;
    • Ewing, Rebecca;
    • Floyd, Yvonne;
    • Gray, Kristian;
    • Hall, Sarah;
    • Hawes, Rachel;
    • Hughes, Jaime;
    • Kosmidou, Vivian
    Publication type:
    Article

  • Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adults.

    Published in:
    Genes, Chromosomes & Cancer, 2006, v. 45, n. 1, p. 42, doi. 10.1002/gcc.20265
    By:
    • Graham Bignell;
    • Raffaella Smith;
    • Chris Hunter;
    • Philip Stephens;
    • Helen Davies;
    • Chris Greenman;
    • Jon Teague;
    • Adam Butler;
    • Sarah Edkins;
    • Claire Stevens;
    • Sarah O'Meara;
    • Adrian Parker;
    • Tim Avis;
    • Syd Barthorpe;
    • Lisa Brackenbury;
    • Gemma Buck;
    • Jody Clements;
    • Jennifer Cole;
    • Ed Dicks;
    • Ken Edwards
    Publication type:
    Article

  • Corrigendum: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

    Published in:
    2012
    By:
    • Varela, Ignacio;
    • Tarpey, Patrick;
    • Raine, Keiran;
    • Huang, Dachuan;
    • Ong, Choon Kiat;
    • Stephens, Philip;
    • Davies, Helen;
    • Jones, David;
    • Lin, Meng-Lay;
    • Teague, Jon;
    • Bignell, Graham;
    • Butler, Adam;
    • Cho, Juok;
    • Dalgliesh, Gillian L.;
    • Galappaththige, Danushka;
    • Greenman, Chris;
    • Hardy, Claire;
    • Jia, Mingming;
    • Latimer, Calli;
    • Lau, KingWai
    Publication type:
    Erratum

  • The driver landscape of sporadic chordoma.

    Published in:
    Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01026-0
    By:
    • Tarpey, Patrick S.;
    • Behjati, Sam;
    • Young, Matthew D.;
    • Martincorena, Inigo;
    • Alexandrov, Ludmil B.;
    • Farndon, Sarah J.;
    • Guzzo, Charlotte;
    • Hardy, Claire;
    • Latimer, Calli;
    • Butler, Adam P.;
    • Teague, Jon W.;
    • Shlien, Adam;
    • Futreal, P. Andrew;
    • Shah, Sohrab;
    • Bashashati, Ali;
    • Jamshidi, Farzad;
    • Nielsen, Torsten O.;
    • Huntsman, David;
    • Baumhoer, Daniel;
    • Brandner, Sebastian
    Publication type:
    Article

  • Mining cancer genomes in COSMIC.

    Published in:
    2012
    By:
    • Jia, Mingming;
    • Forbes, Simon A.;
    • Beare, David;
    • Bindal, Nidhi;
    • Gunasekaran, Prasad;
    • Leung, Kenric;
    • Kok, Chai Yin;
    • Bamford, Sally;
    • Cole, Charlotte;
    • Ward, Sari;
    • Teague, Jon;
    • Stratton, Michael R.;
    • Campbell, Peter;
    • Futreal, Andrew
    Publication type:
    Abstract