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- Title
Report of 2 Novel Presentations of Subcutaneous Fat Necrosis of the Newborn.
- Authors
Kannenberg, Susanna M.H.; Jordaan, H. Francois; Visser, Willem I.; Ahmed, Fatima; Bezuidenhout, A. Fourie
- Abstract
Subcutaneous fat necrosis of the newborn (SCFNN) is a rare form of panniculitis classically affecting healthy full-term infants. There are a number of predisposing factors including perinatal asphyxia. The condition generally has a benign course with spontaneous resolution, but monitoring for metabolic complications, in particular the potentially life-threatening complication of hypercalcaemia, is critical. The authors report 2 cases of preterm infants with perinatal asphyxia with atypical presentations of SCFNN: the first with bony involvement resembling Langerhans cell histiocytosis and with follicular pseudocarcinomatous hyperplasia on histology; and the second presenting with a huge haematoma requiring surgical debridement. Both cases were initially erroneously diagnosed as pyogenic infections.
- Subjects
ASPHYXIA neonatorum; LANGERHANS-cell histiocytosis; NECROSIS; PREMATURE infants; DISEASE complications
- Publication
Dermatopathology, 2019, Vol 6, Issue 2, p147
- ISSN
2296-3529
- Publication type
Article
- DOI
10.1159/000497176