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- Title
Occupational exposures and mortality from cardiovascular disease among women textile workers in Shanghai, China.
- Authors
Gallagher, Lisa G.; Ray, Roberta M.; Li, Wenjin; Psaty, Bruce M.; Gao, Dao Li; Thomas, David B.; Checkoway, Harvey
- Abstract
Background Exposure to textile fiber dusts, like particulate air pollution, may be associated with cardiovascular disease (CVD) mortality. Bacterial endotoxin, a potent inflammagen found in cotton dust, may be a specific risk factor. Methods Female textile workers (N = 267,400) in Shanghai, China were followed for CVD mortality (1989-2000). Factory exposures were approximated by sector classifications based on materials and processes. Quantitative endotoxin and cotton dust measures were available for a subcohort (n = 3,188). Cox proportional hazards modeling was used to estimate hazard ratios (HR) and 95% confidence interval (CI). Results Slightly elevated mortality risk for the cotton sector was seen for ischemic stroke (HR = 1.12, 95% CI: 0.97-1.31) and hemorrhagic stroke (HR = 1.12, 95% CI: 1.02-1.23). Similar hemorrhagic stroke mortality risk was observed in high dust sectors (HR = 1.12, 95% CI: 1.02-1.24). No association was observed for ischemic heart disease. Conclusions Exposures in textile factories may have contributed to CVD mortality among this cohort. The specific components of these exposures that may be harmful are not clear and should be further investigated. Am. J. Ind. Med. 55:991-999, 2012. © 2012 Wiley Periodicals, Inc.
- Subjects
DEATH (Biology); MORTALITY; WOMEN'S health; PERSONNEL management; HEART diseases in women
- Publication
American Journal of Industrial Medicine, 2012, Vol 55, Issue 11, p991
- ISSN
0271-3586
- Publication type
Article
- DOI
10.1002/ajim.22113