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- Title
cDNA cloning of a new member of the Ras superfamily, RAB9-like, on the human chromosome Xq22.1-q22.3 region.
- Authors
Seki, N.; Azuma, T.; Yoshikawa, T.; Masuho, Y.; Muramatsu, M.; Saito, T.
- Abstract
Abstract Members of the RAB protein family regulate vesicular trafficking and reside in specific intercellular compartments. A new member of the RAB family was identified through a public database search, and its full-length cDNA was isolated from a human fetal brain cDNA library. The predicted protein product of the gene consists of 201 amino acid residues, and the protein has 86% similarity to human RAB9 at the amino acid level. We designated the new gene RAB9-like. Northern blot analysis showed that the gene was transcribed ubiquitously in various human tissues. A database search revealed that the gene is divided into three exons and spans approximately 7.2kb of the genome DNA of chromosome Xq22.1-q22.3 region.
- Subjects
FETAL brain; AMINO acids; EXONS (Genetics); DNA; CHROMOSOMES
- Publication
Journal of Human Genetics, 2000, Vol 45, Issue 5, p318
- ISSN
1434-5161
- Publication type
Article
- DOI
10.1007/s100380070025