We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Clinical Manifestations and Molecular Diagnosis of Scrub Typhus and Murine Typhus, Vietnam, 2015-2017.
- Authors
Nguyen Vu Trung; Le Thi Hoi; Vu Minh Dien; Dang Thi Huong; Tran Mai Hoa; Vu Ngoc Lien; Phan Van Luan; Lewycka, Sonia Odette; Choisy, Marc; Bryant, Juliet E.; Nadjm, Behzad; van Doorn, H. Rogier; Richards, Allen L.; Nguyen Van Kinh; Trung, Nguyen Vu; Hoi, Le Thi; Dien, Vu Minh; Huong, Dang Thi; Hoa, Tran Mai; Lien, Vu Ngoc
- Abstract
Rickettsioses are endemic to Vietnam; however, only a limited number of clinical studies have been performed on these vectorborne bacteria. We conducted a prospective hospital-based study at 2 national referral hospitals in Hanoi to describe the clinical characteristics of scrub typhus and murine typhus in northern Vietnam and to assess the diagnostic applicability of quantitative real-time PCR assays to diagnose rickettsial diseases. We enrolled 302 patients with acute undifferentiated fever and clinically suspected rickettsiosis during March 2015-March 2017. We used a standardized case report form to collect clinical information and laboratory results at the time of admission and during treatment. We confirmed scrub typhus in 103 (34.1%) patients and murine typhus in 12 (3.3%) patients. These results highlight the need for increased emphasis on training for healthcare providers for earlier recognition, prevention, and treatment of rickettsial diseases in Vietnam.
- Subjects
VIETNAM; HANOI (Vietnam); TSUTSUGAMUSHI disease; RICKETTSIAL diseases; MOLECULAR diagnosis
- Publication
Emerging Infectious Diseases, 2019, Vol 25, Issue 4, p633
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2504.180691