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Treatments for behavioural disorders in neurodegenerative diseases: drug development strategies.
- Published in:
- Nature Reviews Drug Discovery, 2006, v. 5, n. 1, p. 64, doi. 10.1038/nrd1928
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- Publication type:
- Article
Strategies for analysing behavioural data in clinical trials involving patients with Alzheimer's disease.
- Published in:
- International Journal of Neuropsychopharmacology, 1999, v. 2, n. 1, p. 59, doi. 10.1017/s1461145799001340
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- Publication type:
- Article
A Chromatographic Screening Method to Identify Agents that Reverse Intrinsic Drug Resistance in Colon Cancer Cells.
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- LC-GC Europe, 2006, v. 19, n. 6, p. 363
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- Publication type:
- Article
Effect of Donepezil on Cognition in Severe Alzheimer's Disease: A Pooled Data Analysis.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 21, n. 3, p. 843, doi. 10.3233/JAD-2010-100078
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- Publication type:
- Article
PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses.
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- Journal of Alzheimer's Disease, 2010, v. 20, n. 2, p. 509, doi. 10.3233/JAD-2010-1390
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- Publication type:
- Article
Effects of Rivastigmine in Alzheimer's Disease Patients with and Without Hallucinations.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 20, n. 1, p. 301, doi. 10.3233/JAD-2010-1362
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- Publication type:
- Article
Mary S. Easton Center of Alzheimer's Disease Research at UCLA: Advancing the Therapeutic Imperative.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 19, n. 2, p. 375, doi. 10.3233/JAD-2010-1286
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- Publication type:
- Article
Rivastigmine in Dementia Associated with Parkinson's Disease and Alzheimer's Disease: Similarities and Differences.
- Published in:
- Journal of Alzheimer's Disease, 2007, v. 11, n. 4, p. 509, doi. 10.3233/JAD-2007-11412
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- Publication type:
- Article
Clinical evaluation as a biomarker for Alzheimer's disease.
- Published in:
- Journal of Alzheimer's Disease, 2005, v. 8, n. 4, p. 327
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- Publication type:
- Article
Mild cognitive impairment (MCI) represents early-stage Alzheimer's disease.
- Published in:
- 2005
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- Publication type:
- journal article
A Conformation Variant of p53 Combined with Machine Learning Identifies Alzheimer Disease in Preclinical and Prodromal Stages.
- Published in:
- Journal of Personalized Medicine, 2021, v. 11, n. 1, p. 14, doi. 10.3390/jpm11010014
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- Publication type:
- Article
Distinguishing apathy from depression: A review differentiating the behavioral, neuroanatomic, and treatment‐related aspects of apathy from depression in neurocognitive disorders.
- Published in:
- International Journal of Geriatric Psychiatry, 2023, v. 38, n. 2, p. 1, doi. 10.1002/gps.5882
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- Publication type:
- Article
Potential beneficial effects of masupirdine (SUVN-502) on agitation/aggression and psychosis in patients with moderate Alzheimer's disease: Exploratory post hoc analyses.
- Published in:
- 2022
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- Publication type:
- journal article
Sex Moderates Amyloid and Apolipoprotein ε4 Effects on Default Mode Network Connectivity at Rest.
- Published in:
- Frontiers in Neurology, 2019, p. 1, doi. 10.3389/fneur.2019.00900
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- Publication type:
- Article
Alzheimer Disease.
- Published in:
- JAMA: Journal of the American Medical Association, 2002, v. 287, n. 18, p. 2335, doi. 10.1001/jama.287.18.2335
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- Publication type:
- Article
Positron Emission Tomography in Evaluation of Dementia.
- Published in:
- JAMA: Journal of the American Medical Association, 2001, v. 286, n. 17, p. 2120, doi. 10.1001/jama.286.17.2120
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- Publication type:
- Article
Understanding Parkinson disease.
- Published in:
- 1999
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- Publication type:
- commentary
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain.
- Published in:
- 2020
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- Publication type:
- journal article
Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network.
- Published in:
- Brain: A Journal of Neurology, 2015, v. 138, n. 4, p. 1036, doi. 10.1093/brain/awv004
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- Publication type:
- Article
Scenarios for the long‐term efficacy of amyloid‐targeting therapies in the context of the natural history of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 6374, doi. 10.1002/alz.14134
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- Publication type:
- Article
Care partner‐informed meaningful change thresholds for the Clinical Dementia Rating‐Sum of Boxes for trials of early Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 5889, doi. 10.1002/alz.14050
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- Publication type:
- Article
Generating real‐world evidence in Alzheimer's disease: Considerations for establishing a core dataset.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4331, doi. 10.1002/alz.13785
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- Publication type:
- Article
Impact of the iWHELD digital person‐centered care program on quality of life, agitation and psychotropic medications in people with dementia living in nursing homes during the COVID‐19 pandemic: A randomized controlled trial.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 1797, doi. 10.1002/alz.13582
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- Publication type:
- Article
Microglial immunometabolism endophenotypes contribute to sex difference in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1334, doi. 10.1002/alz.13546
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- Publication type:
- Article
Blood‐based biomarker profiles of community cohort of rural‐dwelling older adults.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083167
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- Publication type:
- Article
GRADUATE I AND II: Revisiting the key findings from two Phase III studies evaluating the efficacy and safety of subcutaneous gantenerumab in early Alzheimer's disease (AD).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082977
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- Publication type:
- Article
The Therapeutic Landscape of Tauopathies: Evaluating the Tau Pipeline.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.077879
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- Publication type:
- Article
Design of a Phase 2, Randomized, Double‐Blind, Placebo‐Controlled, Parallel‐Group Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Subjects with Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease Dementia
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.077322
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- Publication type:
- Article
Dementia with Lewy bodies Drug Therapies in Clinical Trials: 2022.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.077429
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- Publication type:
- Article
UPREGULATING ABCA1‐MEDIATED CHOLESTEROL TRANSPORTATION BY CS6253 – OPPORTUNITY FOR CONVENIENT SC ROUTE OF ADMINISTRATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076868
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- Publication type:
- Article
Design of ADEPT‐2, a phase 3, parallel group study to evaluate KarXT [xanomeline‐trospium] as a treatment for psychosis associated with Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.075201
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- Publication type:
- Article
Interpreting trial results in an era of disease‐modifying therapies: Efficacy of approved anti‐amyloid drugs in the context of the long‐term Alzheimer's trajectory.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.074550
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- Publication type:
- Article
Mapping of validated apathy scales onto the apathy diagnostic criteria for neurocognitive disorders.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079997
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- Publication type:
- Article
Amyloidosis at Putamen Predicts Vulnerability to Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079343
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- Publication type:
- Article
Florbetapir amyloid PET in cognitively impaired former professional and college American football players.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077854
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- Publication type:
- Article
Early Detection of Alzheimer's Disease using microRNAs.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077745
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- Publication type:
- Article
Discovery of disease‐associated, tau, and inflammatory microglial subpopulations and molecular drivers in Alzheimer's disease using network‐based deep learning integration of human brain single‐cell RNA‐sequencing data.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074328
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- Publication type:
- Article
Alzheimer's disease genetics and real‐world patient data fuel target and drug discovery in European and African American ancestries.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074333
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- Publication type:
- Article
Multimodal omics analytic framework identifies microglial immunometabolism endophenotypes underlying sex differences in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074320
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- Publication type:
- Article
Amyloidosis at Putamen Predicts Vulnerability to Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081896
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- Publication type:
- Article
Alzheimer's disease genetics and real‐world patient data fuel target and drug discovery in European and African American ancestries.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074333
- By:
- Publication type:
- Article
Discovery of disease‐associated, tau, and inflammatory microglial subpopulations and molecular drivers in Alzheimer's disease using network‐based deep learning integration of human brain single‐cell RNA‐sequencing data.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074328
- By:
- Publication type:
- Article
Multimodal omics analytic framework identifies microglial immunometabolism endophenotypes underlying sex differences in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074320
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- Publication type:
- Article
Interaction effect of sex and diagnosis on functional connectivity within the default network in healthy controls, mild cognitive impairment and Alzheimer Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.068142
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- Publication type:
- Article
Increased spatial extent of cerebral tau PET elevations in former NFL and college football players from the DIAGNOSE CTE Research Project.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.060872
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- Publication type:
- Article
Population‐based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 5, p. 1876, doi. 10.1002/alz.12819
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- Publication type:
- Article
Why a clinical trial is as good as its outcome measure: A framework for the selection and use of cognitive outcome measures for clinical trials of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 2, p. 708, doi. 10.1002/alz.12773
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- Publication type:
- Article
Population‐based Discovery and Ethnically Mixed Mendelian Randomization Validation Identifies Telmisartan as a Candidate Drug for Alzheimer's Disease in African Americans.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.066634
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- Publication type:
- Article
evoke and evoke+: design of two large‐scale, double‐blind, placebo‐controlled, phase 3 studies evaluating the neuroprotective effects of semaglutide in early Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.062415
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- Publication type:
- Article
Efficacy and safety of pimavanserin in patients with Alzheimer's dementia psychosis in the HARMONY phase 3, randomized discontinuation study: a post hoc subgroup analysis.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.062364
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- Publication type:
- Article