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- Title
An Update on Orthobiologics: Cautious Optimism.
- Authors
Nelson, Patrick A.; George, Tom; Bowen, Edward; Sheean, Andrew J.; Bedi, Asheesh
- Abstract
Orthobiologics are rapidly growing in use given their potential to augment healing for multiple musculoskeletal conditions. Orthobiologics consist of a variety of treatments including platelet-rich plasma and stem cells that provide conceptual appeal in providing local delivery of growth factors and inflammation modulation. The lack of standardization in nomenclature and applications within the literature has led to a paucity of high-quality evidence to support their frequent use. The purpose of this review was to describe the current landscape of orthobiologics and the most recent evidence regarding their use.
- Subjects
BONE marrow physiology; PLATELET-rich plasma; MUSCULOSKELETAL system diseases; WOUND healing; TENDINOPATHY; BIOLOGICAL products; INFLAMMATION; MEDICAL care costs; CONTINUING education units; STEM cells; MUSCULOSKELETAL pain; COST effectiveness; OSTEOARTHRITIS; ORTHOPEDICS; ROTATOR cuff; MENISCUS injuries
- Publication
American Journal of Sports Medicine, 2024, Vol 52, Issue 1, p242
- ISSN
0363-5465
- Publication type
Article
- DOI
10.1177/03635465231192473