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- Title
Molecular Testing in Thyroid Cancer.
- Authors
Cappola, Anne R.; Mandel, Susan J.
- Abstract
The article presents insights on a study of individuals with papillary thyroid cancer (PTC). Particular focus is given to the testing for a mutation in the BRAF gene that has been previously linked with multiple features of aggressive PTC. According to the authors, the analyses indicate that the mutation mediates features of the clinically aggressive tumors that account for PTC mortality. They add that BRAF testing does not provide predictive value for PTC-related mortality.
- Subjects
THYROID cancer; GENETIC mutation; CANCER genetics; CANCER-related mortality; GENETIC testing; HUMAN chromosome abnormality diagnosis
- Publication
JAMA: Journal of the American Medical Association, 2013, Vol 309, Issue 14, p1529
- ISSN
0098-7484
- Publication type
Editorial
- DOI
10.1001/jama.2013.3620