We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Estimating the Health and Economic Impact of Improved Management in Prevalent Chronic Obstructive Pulmonary Disease Populations in England, Germany, Canada, and Japan: A Modelling Study.
- Authors
Adams, Elisabeth J; van Doornewaard, Alexander; Ma, Yixuan; Ahmed, Nurilign; Cheng, Man Ki; Watz, Henrik; Ichinose, Masakazu; Wilkinson, Tom; Bhutani, Mohit; Licskai, Christopher J; Turner, Katy M E
- Abstract
To estimate the potential health and economic impact of improved adherence to guideline-recommended care for prevalent, on-treatment COPD populations in four high-income settings.Methods: A disease simulation model was developed to evaluate the impact of theoretical improvements to COPD management, comparing outcomes for usual care and policy scenarios for interventions that reduce avoidable hospitalisations: 1) increased attendance (50% vs 31– 38%) of early follow-up review after severe exacerbation hospitalisation; 2) increased access (30% vs 5– 10%) to an integrated disease management (IDM) programme that provides guideline adherent care.Results: For cohorts of 100,000 patients, Policy 1 yielded additional life years (England: 523; Germany: 759; Canada: 1316; Japan: 512) and lifetime cost savings (-£ 2.89 million; -€ 6.58 million; -$40.08 million; -¥ 735.58 million). For Policy 2, additional life years (2299; 3619; 3656) and higher lifetime total costs (£ 38.15 million; € 35.58 million; ¥ 1091.53 million) were estimated in England, Germany and Japan, and additional life years (4299) and cost savings (-$20.52 million) in Canada. Scenarios found that the cost impact depended on the modelled intervention effect size.Conclusion: Interventions that reduce avoidable hospitalisations are estimated to improve survival and may generate cost savings. This study provides evidence on the theoretical impact of policies to improve COPD care and highlights priority areas for further research to support evidence-based policy decisions.
- Publication
International Journal of COPD, 2023, Vol 18, p2127
- ISSN
1176-9106
- Publication type
Article
- DOI
10.2147/COPD.S416988