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- Title
Hidroacanthoma simplex: An ultrastructural and immunohistochemical study.
- Authors
Perniciaro, Charles; Muller, Sigfrid A.; Zelickson, Brian D.; Snow, John L.
- Abstract
A representative case of hidroacanthoma simplex was studied with routine light microscopy, immunohistochemistry, and electron microscopy. Staining with the periodic acid-Schiff reagent and immunostaining with anti-keratin antibodies were useful in demarcating the tumor cells from adjacent normal epithelium. However, antibodies to carcinoembryonic antigen and epithelial membrane antigen did not help us to segregate or identify the neoplastic cells. Electron microscopy revealed tumor cells markedly different in appearance from luminal cells of the acrosyringium. Hidroacanthoma simplex does not appear to be derived from luminal cells of the acrosyringium. We propose criteria for the histologic diagnosis of this benign neoplasm.
- Subjects
IMMUNOGLOBULINS; MICROSCOPY; TUMORS; EPITHELIUM; CARCINOEMBRYONIC antigen; ONCOLOGY
- Publication
Journal of Cutaneous Pathology, 1994, Vol 21, Issue 3, p274
- ISSN
0303-6987
- Publication type
Article
- DOI
10.1111/j.1600-0560.1994.tb00273.x