We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Hipervitaminosis B<sub>12</sub> persistente.
- Authors
García Rodríguez, Ana María; Sánchez Velasco, Miguel J.
- Abstract
Persistent hypervitaminosis B12 is an incidental and unexpected finding of elevated levels of vitamin B12 in a blood test. It can be caused by various conditions, ranging from insignificant causes to being a marker of silent neoplasia, liver, kidney, immune, or infectious disease. It is important to rule out pathologies and observe the evolution over time. Sustained elevation of vitamin B12 without apparent causes should not be underestimated and can be a prognostic and survival marker in patients with malnutrition, established cancer, and critical situations. The concurrent elevation of homocysteine and methylmalonic acid indicates a deficiency in the bioavailability of cobalamin at the tissue level. The article discusses the necessary tests to reach a diagnosis of hypervitaminosis B12 and its management in primary care.
- Subjects
VITAMIN B12; METHYLMALONIC acid; VITAMIN B12 deficiency; PROGNOSIS; BLOOD testing
- Publication
AMF: Actualización en Medicina de Familia, 2022, Vol 18, Issue 9, p520
- ISSN
1699-9029
- Publication type
Article