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- Title
Practice of Comparative Effectiveness Research to Identify Treatment Characteristics of Similar Chinese Patent Medicine for Angina Pectoris.
- Authors
Cao, Hongbo; Wang, Ping; Li, Nan; Liu, Dan; Ma, Junshao; Fan, Ruihong; Zhou, Zhihuan
- Abstract
Objective. Individualized application of TCM is not easy and may lead to undesirable results, such as poor effect or even adverse reactions. This trial aims to compare two common Chinese patent medicines with similar effects. Background of the Research. Four hospitals carried out the test at the same time in Tianjin city of China. Participants. 144 patients were involved in this study; all patients must meet the diagnostic criteria. Interventions. Qishen Yiqi pills, compound danshen pills, and their placebos; an efficacy analysis was conducted after the first medication and after crossover medication. Primary Outcome Measures. The primary index of end point includes Seattle Angina Questionnaire score-7 and score of 7-point Likert Scale; the curative effect was compared with minimal clinically important differences value. Result. Two drugs have their respective advantages in treating SAP. In practical application, the two drugs shall be discriminated in use based on patients’ specific symptoms. Trial Registration. Chinese clinical trials register is <ext-link>ChiCTR-TTRCC-14004406</ext-link> (registered 23 March 2014).
- Subjects
CHINA; DRUG therapy for angina pectoris; CLINICAL trials; HERBAL medicine; RESEARCH methodology; MEDICAL cooperation; CHINESE medicine; HEALTH outcome assessment; QUESTIONNAIRES; RESEARCH; SCALE analysis (Psychology); CLINICAL trial registries
- Publication
Evidence-based Complementary & Alternative Medicine (eCAM), 2017, Vol 2017, p1
- ISSN
1741-427X
- Publication type
Article
- DOI
10.1155/2017/7062714