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- Title
Thermoresponsive Behavior of Magnetic Nanoparticle Complexed pNIPAm-co-AAc Microgels.
- Authors
Lee, Su-Kyoung; Park, Yongdoo; Kim, Jongseong
- Abstract
Featured Application: This work will provide a simple route for potential applications of magnetic nanoparticle–hydrogel complex in temperature responsive behaviors. It will be worthwhile to employ this work to develop thermoresponsive magnetic resonance imaging agent and magneto-thermo induced stimulation toolkits for cell regulation. Characterization of responsive hydrogels and their enhancement with novel moieties have improved our understanding of functional materials. Hydrogels coupled with inorganic nanoparticles have been sought for novel types of responsive materials, but the efficient routes for the formation and the responsivity of complexed materials remain for further investigation. Here, we report that responsive poly(N-isopropylacrylamide-co-acrylic acid) (pNIPAm-co-AAc) hydrogel microparticles (microgels) are tunable by varying composition of co-monomer and crosslinker as well as by their complexation with magnetic nanoparticles in aqueous dispersions. Our results show that the hydrodynamic diameter and thermoresponsivity of microgels are closely related with the composition of anionic co-monomer, AAc and crosslinker, N,N′-Methylenebisacrylamide (BIS). As a composition of hydrogels, the higher AAc increases the swelling size of the microgels and the volume phase transition temperature (VPTT), but the higher BIS decreases the size with no apparent effect on the VPTT. When the anionic microgels are complexed with amine-modified magnetic nanoparticles (aMNP) via electrostatic interaction, the microgels decrease in diameter at 25 °C and shift the volume phase transition temperature (VPTT) to a higher temperature. Hysteresis on the thermoresponsive behavior of microgels is also measured to validate the utility of aMNP-microgel complexation. These results suggest a simple, yet valuable route for development of advanced responsive microgels, which hints at the formation of soft nanomaterials enhanced by inorganic nanoparticles.
- Subjects
THERMORESPONSIVE polymers; MAGNETIC nanoparticles; MICROGELS
- Publication
Applied Sciences (2076-3417), 2018, Vol 8, Issue 10, p1984
- ISSN
2076-3417
- Publication type
Article
- DOI
10.3390/app8101984