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- Title
Review on marine collagen peptides induce cancer cell apoptosis, necrosis, and autophagy by reducing oxidized free radicals.
- Authors
YINGHUA LUO; YU ZHANG; TONG ZHANG; YANNAN LI; HUI XUE; JINGLONG CAO; WENSHUANG HOU; JIAN LIU; YUHE CUI; TING XU; CHENGHAO JIN
- Abstract
Marine collagen peptides (MCPs) are natural products prepared by hydrolyzing marine collagen protein through a variety of chemical methods or enzymes. MCPs have a range of structures and biological activities and are widely present in marine species. MCPs also have a small molecular weight, are easily modified, and absorbed by the body. These properties have attracted great interest from researchers studying antioxidant, anti-tumor, and anti-aging activities. MCPs of specific molecular weights have significant anti-tumor activity and no toxic side effects. Thus, MCPs have the potential use as anti-cancer adjuvant drugs. Free radicals produced by oxidation are closely related to human aging, cancer, arteriosclerosis, and other diseases, but their relationship with cancer is not well known. In this review, we focus on the antioxidant properties of MCPs in the treatment of cancer, highlighting their antioxidant molecular structure and potential for clinical practice.
- Subjects
PEPTIDES; CANCER cells; APOPTOSIS; NECROSIS; AUTOPHAGY; FREE radicals
- Publication
Biocell, 2023, Vol 47, Issue 5, p965
- ISSN
0327-9545
- Publication type
Article
- DOI
10.32604/biocell.2023.027729