We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
The UCLA population studies of CORD: X. A cohort study of change in respiratory function Associated with Chronic Exposure to SOx, NOx, and Hydrocarbons.
- Authors
Detels, Roger; Tashkin, Donald P.; Sayre, James W.; Rokaw, Stanley N.; Frank J. Massey Jr.; Coulson, Anne H.; Wegman, David H.
- Abstract
Two never-smoking cohorts in Southern California, one in Lancaster (N = 2340) exposed only to moderate levels of oxidants and the other in Long Beach (N = 1326) exposed to high levels of SOx, NO2, hydrocarbons and particulates completed spirometry and the single-breath nitrogen test five to six years apart. Forty-seven percent and 45 percent of the participants were retested. Mean results at baseline for those tested and not retested were similar. Loss to follow-up was primarily the moving (39 percent and 47 percent). Every difference of consequence indicated greater deterioration in lung function in Long Beach. The level of significance of the difference was greatest, even in the youngest age groups, for ΔN2750-1290, suggesting that the earliest site of impairment may occur in the small airways. Greater deterioration in spirometric parameters was observed in every age group in Long Beach females above seven years of age at baseline and in Long Beach males above 15 years of age, suggesting that chronic exposure to the pollutant mix occuring in Long Beach ultimately adversely affects the large airways as well as small airways.
- Subjects
LOS Angeles (Calif.); CALIFORNIA; RESPIRATORY measurements; COHORT analysis; POPULATION research; UNIVERSITY of California, Los Angeles; HYDROCARBONS; SPIROMETRY; AGE groups; LUNGS
- Publication
American Journal of Public Health, 1991, Vol 81, Issue 3, p350
- ISSN
0090-0036
- Publication type
Article
- DOI
10.2105/AJPH.81.3.350