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- Title
Hepatitis tóxica como manifestación de la intoxicación por dióxido de cloro como uso profiláctico contra la infección por el virus SARS-CoV-2.
- Authors
Martínez-Camacho, Heriberto; Morfín, Lorena; Brito, Arabela; Cruz, Brandon
- Abstract
BACKGROUND: In the framework of the COVID-19 pandemic, some miracle products have emerged as part of the disease therapy, one of them has been chlorine dioxide and its derivatives. The Pan American Health Organization (PAHO), the European Medicines Agency (AEM) and the US Food and Drug Administration (FDA) have prepared and issued statements warning about the lack of scientific evidence in relation to its efficacy in disease caused by SARS-CoV-2 and on risks to human health. CLINICAL CASE: A 62-year-old female, with a previous history of jaundice not studied. She presented a 3-week evolution with mesogastric colic pain and generalized jaundice, associated with the ingestion of chlorine dioxide during the 3 previous months. Liver function tests: TGO: 2316 U/L, TGP: 1449 U/L, FA: 531.2 U/L, BBT: 10.41 mg/dL, BBD: 7.14 mg/dL, BBI: 3.27 mg/dL; liver ultrasound reported degenerative liver disease. Liver biopsy was compatible with toxic "drug" hepatitis. CONCLUSIONS: Chlorine dioxide belongs to a list of products that have been promoted without scientific support as prophylactic or therapeutic agents for the management of SARS-CoV-2 disease; however, the absence of evidence on its usefulness and the development of adverse effects, such as liver toxicity, have been documented in this and other publications; thus, it is recommended to avoid its administration.
- Publication
Medicina Interna de Mexico, 2022, Vol 38, Issue 5, p1132
- ISSN
0186-4866
- Publication type
Article
- DOI
10.24245/mim.v38i5.7045