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- Title
Comparison of the analgesic effects of meloxicam and carprofen administered preoperatively to dogs undergoing orthopaedic surgery.
- Authors
Laredo, F. G.; Belda, E.; Murciano, J.; Escobar, M.; Navarro, A.; Robinson, K. J.; Jones, R. S.
- Abstract
Thirty-two dogs undergoing operations to repair a torn cranial cruciate ligament or a fractured long bone were randomly allocated to one of two treatment groups in a study on pestoperative pain. Sixteen of the dogs were given 4 mg/kg carprofen and the other 16 were given 0.2 mg/kg meloxicam subcutaneously before the operation. The signs of pain shown by the animals were assessed for 24 hours on a visual analogue scale, a discontinuous scoring system, and a score based on five behavioural and physiological variables. The dogs' heart and respiratory rates and their mean arterial blood pressures were also measured non-invasively at each assessment. Blood samples were taken before the surgery and 24 hours after it, and the concentrations of urea and creatinine were measured in plasma. Both drugs were effective in relieving the signs of pain for up to 24 hours in all the dogs. There were no significant changes in the concentrations of urea and creatinine, and no adverse effects were reported during the postoperative period.
- Subjects
DRUG efficacy; ORTHOPEDIC surgery; POSTOPERATIVE pain; ANALGESIA; DOGS
- Publication
Veterinary Record: Journal of the British Veterinary Association, 2004, Vol 155, Issue 21, p667
- ISSN
0042-4900
- Publication type
Article
- DOI
10.1136/vr.155.21.667