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- Title
Granulocytic sarcoma preceding acute leukemia: a report of six cases.
- Authors
Krause, John R.; Krause, J R
- Abstract
An unusual case of granulocytic sarcoma presenting in a pericardial effusion following trauma and preceding acute myelogenous leukemia (AML) by 8 months is presented. Five additional cases of granulocytic sarcoma preceding leukemia collected by the author are also tabulated. Granulocytic sarcoma in a nonautopsy population of myelogenous leukemic patients was found to be 2.9%. When presenting in an extramedullary site, especially preceding peripheral blood and bone marrow manifestations of leukemia, a misdiagnosis of histiocytic lymphoma may result. In questionable cases, other techniques including the naphthol-ASD-chloroacetate stain, touch imprints, immunoperoxidase stain for lysozyme, and electron microscopy should be utilized. Although only a small series, the most recent cases have shown induction/remission and survival characteristics of AML patients without granulocytic sarcoma.
- Publication
Cancer (0008543X), 1979, Vol 44, Issue 3, p1017
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(197909)44:3<1017::AID-CNCR2820440333>3.0.CO;2-I