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IL13Rα2 expression identifies tissue‐resident IL‐22‐producing PLZF<sup>+</sup> innate T cells in the human liver.
Published in:
European Journal of Immunology, 2018, v. 48, n. 8, p. 1329, doi. 10.1002/eji.201747334
By:
- Paquin‐Proulx, Dominic;
- Greenspun, Benjamin C.;
- Pasquet, Lise;
- Strunz, Benedikt;
- Aleman, Soo;
- Falconer, Karolin;
- Terabe, Masaki;
- Berzofsky, Jay A.;
- Sandberg, Johan K.;
- Melum, Espen;
- Nixon, Douglas F.;
- Björkström, Niklas K.
Publication type:
Article
Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients.
Published in:
Digestive Diseases & Sciences, 2024, v. 69, n. 10, p. 3810, doi. 10.1007/s10620-024-08570-y
By:
- Frank, Anna Katharina;
- Chung, Brian K.;
- De Novales, Miguel Larraz Lopez;
- Engesæter, Lise Katrine;
- Hoyle, Henry William;
- Øgaard, Jonas;
- Heslop, James;
- Karlsen, Tom H.;
- Tysoe, Olivia;
- Brevini, Teresa;
- Tchorz, Jan S.;
- Vallier, Ludovic;
- Mohorianu, Irina;
- Sampaziotis, Fotios;
- Melum, Espen
Publication type:
Article
The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation.
Published in:
Physiological Reports, 2017, v. 5, n. 4, p. 1, doi. 10.14814/phy2.13117
By:
- Schrumpf, Elisabeth;
- Jiang, Xiaojun;
- Zeissig, Sebastian;
- Pollheimer, Marion J.;
- Anmarkrud, Jarl Andreas;
- Tan, Corey;
- Exley, Mark A.;
- Karlsen, Tom H.;
- Blumberg, Richard S.;
- Melum, Espen
Publication type:
Article
From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software.
Published in:
Nucleic Acids Research, 2013, v. 41, n. 1, p. e16, doi. 10.1093/nar/gks836
By:
- Forster, Michael;
- Forster, Peter;
- Elsharawy, Abdou;
- Hemmrich, Georg;
- Kreck, Benjamin;
- Wittig, Michael;
- Thomsen, Ingo;
- Stade, Björn;
- Barann, Matthias;
- Ellinghaus, David;
- Petersen, Britt-Sabina;
- May, Sandra;
- Melum, Espen;
- Schilhabel, Markus B.;
- Keller, Andreas;
- Schreiber, Stefan;
- Rosenstiel, Philip;
- Franke, Andre
Publication type:
Article
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.
Published in:
Nature Biotechnology, 2015, v. 33, n. 8, p. 845, doi. 10.1038/nbt.3275
By:
- Sampaziotis, Fotios;
- Cardoso de Brito, Miguel;
- Madrigal, Pedro;
- Bertero, Alessandro;
- Saeb-Parsy, Kourosh;
- Soares, Filipa A C;
- Schrumpf, Elisabeth;
- Melum, Espen;
- Karlsen, Tom H;
- Bradley, J Andrew;
- Gelson, William T H;
- Davies, Susan;
- Baker, Alastair;
- Kaser, Arthur;
- Alexander, Graeme J;
- Hannan, Nicholas R F;
- Vallier, Ludovic
Publication type:
Article
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
Published in:
Nature Genetics, 2011, v. 43, n. 1, p. 17, doi. 10.1038/ng.728
By:
- Melum, Espen;
- Franke, Andre;
- Schramm, Christoph;
- Weismüller, Tobias J.;
- Gotthardt, Daniel Nils;
- Offner, Felix A.;
- Juran, Brian D.;
- Laerdahl, Jon K.;
- Labi, Verena;
- Björnsson, Einar;
- Weersma, Rinse K.;
- Henckaerts, Liesbet;
- Teufel, Andreas;
- Rust, Christian;
- Ellinghaus, Eva;
- Balschun, Tobias;
- Boberg, Kirsten Muri;
- Ellinghaus, David;
- Bergquist, Annika;
- Sauer, Peter
Publication type:
Article
Scalable production of tissue-like vascularized liver organoids from human PSCs.
Published in:
Experimental & Molecular Medicine EMM, 2023, v. 55, n. 9, p. 2005, doi. 10.1038/s12276-023-01074-1
By:
- Harrison, Sean P.;
- Siller, Richard;
- Tanaka, Yoshiaki;
- Chollet, Maria Eugenia;
- de la Morena-Barrio, María Eugenia;
- Xiang, Yangfei;
- Patterson, Benjamin;
- Andersen, Elisabeth;
- Bravo-Pérez, Carlos;
- Kempf, Henning;
- Åsrud, Kathrine S.;
- Lunov, Oleg;
- Dejneka, Alexandr;
- Mowinckel, Marie-Christine;
- Stavik, Benedicte;
- Sandset, Per Morten;
- Melum, Espen;
- Baumgarten, Saphira;
- Bonanini, Flavio;
- Kurek, Dorota
Publication type:
Article
Refinement of the MHC Risk Map in a Scandinavian Primary Sclerosing Cholangitis Population.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114486
By:
- Næss, Sigrid;
- Lie, Benedicte A.;
- Melum, Espen;
- Olsson, Marita;
- Hov, Johannes R.;
- Croucher, Peter J. P.;
- Hampe, Jochen;
- Thorsby, Erik;
- Bergquist, Annika;
- Traherne, James A.;
- Schrumpf, Erik;
- Boberg, Kirsten Muri;
- Schreiber, Stefan;
- Franke, Andre;
- Karlsen, Tom H.
Publication type:
Article
Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis.
Published in:
PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012403
By:
- Hov, Johannes R.;
- Keitel, Verena;
- Laerdahl, Jon K.;
- Spomer, Lina;
- Ellinghaus, Eva;
- ElSharawy, Abdou;
- Melum, Espen;
- Boberg, Kirsten M.;
- Manke, Thomas;
- Balschun, Tobias;
- Schramm, Christoph;
- Bergquist, Annika;
- Weismüller, Tobias;
- Gotthardt, Daniel;
- Rust, Christian;
- Henckaerts, Liesbet;
- Onnie, Clive M.;
- Weersma, Rinse K.;
- Sterneck, Martina;
- Teufel, Andreas
Publication type:
Article
SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels.
Published in:
BMC Bioinformatics, 2010, v. 11, p. 600, doi. 10.1186/1471-2105-11-600
By:
- Holm, Kristian;
- Melum, Espen;
- Franke, Andre;
- Karlsen, Tom H.
Publication type:
Article
Pathogenesis, diagnosis and treatment of premalignant and malignant stages of cholangiocarcinoma in primary sclerosing cholangitis.
Published in:
Liver International, 2019, v. 39, n. 12, p. 2230, doi. 10.1111/liv.14180
By:
- Grimsrud, Marit M.;
- Folseraas, Trine;
- Melum, Espen
Publication type:
Article
Diagnostic performance of a stepwise cytological algorithm for biliary malignancy in primary sclerosing cholangitis.
Published in:
Liver International, 2019, v. 39, n. 2, p. 382, doi. 10.1111/liv.14007
By:
- Melum, Espen;
- von Seth, Erik;
- Haas, Stephan;
- Bergquist, Annika;
- Arnelo, Urban;
- Ouchterlony, Helena;
- Dobra, Katalin;
- Hjerpe, Anders
Publication type:
Article
Nonalcoholic fatty liver disease is an increasing indication for liver transplantation in the Nordic countries.
Published in:
Liver International, 2018, v. 38, n. 11, p. 2082, doi. 10.1111/liv.13751
By:
- Holmer, Magnus;
- Melum, Espen;
- Isoniemi, Helena;
- Ericzon, Bo‐Göran;
- Castedal, Maria;
- Nordin, Arno;
- Aagaard Schultz, Nicolai;
- Rasmussen, Allan;
- Line, Pål‐Dag;
- Stål, Per;
- Bennet, William;
- Hagström, Hannes
Publication type:
Article
Prognostic biomarkers and surrogate end points in PSC.
Published in:
2016
By:
- Vesterhus, Mette;
- Melum, Espen
Publication type:
Editorial
Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different fromlarge duct disease.
Published in:
Liver International, 2014, v. 34, n. 10, p. 1488, doi. 10.1111/liv.12492
By:
- Næss, Sigrid;
- Björnsson, Einar;
- Anmarkrud, Jarl A.;
- Mamari, Said Al;
- Juran, Brian D.;
- Lazaridis, Konstantinos N.;
- Chapman, Roger;
- Bergquist, Annika;
- Melum, Espen;
- Marsh, Steven G. E.;
- Schrumpf, Erik;
- Lie, Benedicte A.;
- Boberg, Kirsten M.;
- Karlsen, Tom H.;
- Hov, Johannes R.
Publication type:
Article
Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma.
Published in:
International Journal of Cancer, 2008, v. 123, n. 1, p. 241, doi. 10.1002/ijc.23517
By:
- Melum, Espen;
- Buch, Stephan;
- Schafmayer, Clemens;
- Kalthoff, Holger;
- Tepel, Jürgen;
- Schreiber, Stefan;
- Karlsen, Tom H.;
- Hampe, Jochen
Publication type:
Article
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report.
Published in:
World Journal of Surgical Oncology, 2018, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12957-018-1482-7
By:
- Thorgersen, Ebbe Billmann;
- Melum, Espen;
- Folseraas, Trine;
- Larsen, Stein Gunnar;
- Line, Pål Dag
Publication type:
Article
Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973-2030.
Published in:
2017
By:
- Meijerink, Hinta;
- White, Richard A.;
- Løvlie, Astrid;
- de Blasio, Birgitte Freiesleben;
- Dalgard, Olav;
- Amundsen, Ellen J.;
- Melum, Espen;
- Kløvstad, Hilde
Publication type:
journal article
Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.00765
By:
- Xiaojun Jiang;
- Björkström, Niklas K.;
- Melum, Espen
Publication type:
Article
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Published in:
Nature, 2015, v. 517, n. 7534, p. 386, doi. 10.1038/nature13848
By:
- Huang, Yu-Hwa;
- Zhu, Chen;
- Kondo, Yasuyuki;
- Anderson, Ana C.;
- Gandhi, Amit;
- Russell, Andrew;
- Dougan, Stephanie K.;
- Petersen, Britt-Sabina;
- Melum, Espen;
- Pertel, Thomas;
- Clayton, Kiera L.;
- Raab, Monika;
- Chen, Qiang;
- Beauchemin, Nicole;
- Yazaki, Paul J.;
- Pyzik, Michal;
- Ostrowski, Mario A.;
- Glickman, Jonathan N.;
- Rudd, Christopher E.;
- Ploegh, Hidde L.
Publication type:
Article
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice.
Published in:
PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0262821
By:
- Tønnessen, Theis Christian;
- Melleby, Arne Olav;
- Hauge-Iversen, Ida Marie;
- Espe, Emil Knut Stenersen;
- Ahmed, Mohammed Shakil;
- Ueland, Thor;
- Haavardsholm, Espen Andre;
- Atkinson, Sara Marie;
- Melum, Espen;
- Attramadal, Håvard;
- Sjaastad, Ivar;
- Vinge, Leif Erik
Publication type:
Article
Role of bacteria and microbial metabolites in immune modulation during early life.
Published in:
Scandinavian Journal of Immunology, 2024, v. 99, n. 2, p. 1, doi. 10.1111/sji.13336
By:
- Oldereid, Tine Simensen;
- Jiang, Xiaojun;
- Nordhus, Kathrine Sivertsen;
- Ponzetta, Andrea;
- Bjørnholt, Jørgen Vildershøj;
- Björkström, Niklas K.;
- Melum, Espen;
- Rasmussen, Henrik
Publication type:
Article
SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region.
Published in:
Human Mutation, 2010, v. 31, n. 7, p. 875, doi. 10.1002/humu.21276
By:
- Melum, Espen;
- May, Sandra;
- Schilhabel, Markus B.;
- Thomsen, Ingo;
- Karlsen, Tom H.;
- Rosenstiel, Philip;
- Schreiber, Stefan;
- Franke, Andre
Publication type:
Article
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis.
Published in:
Science Translational Medicine, 2021, v. 13, n. 582, p. 1, doi. 10.1126/scitranslmed.abb0036
By:
- Jiang, Xiaojun;
- Bergquist, Annika;
- Löscher, Britt-Sabina;
- Venkatesh, Geetha;
- Mold, Jeff E.;
- Holm, Kristian;
- Laerdahl, Jon K.;
- Skånland, Sigrid S.;
- Maleki, Kimia T.;
- Cornillet, Martin;
- Taskén, Kjetil;
- Franke, Andre;
- Karlsen, Tom H.;
- Björkström, Niklas K.;
- Melum, Espen
Publication type:
Article
Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue.
Published in:
Nature Protocols, 2019, v. 14, n. 6, p. 1884, doi. 10.1038/s41596-019-0168-0
By:
- Tysoe, Olivia C.;
- Justin, Alexander W.;
- Brevini, Teresa;
- Chen, Si Emma;
- Mahbubani, Krishnaa T.;
- Frank, Anna K.;
- Zedira, Hajer;
- Melum, Espen;
- Saeb-Parsy, Kourosh;
- Markaki, Athina E.;
- Vallier, Ludovic;
- Sampaziotis, Fotios
Publication type:
Article
HDAC2 expression and variable number of repeats in exon 1 of the HDAC2 gene in corticotroph adenomas.
Published in:
Clinical Endocrinology, 2010, v. 73, n. 2, p. 229, doi. 10.1111/j.1365-2265.2010.03805.x
By:
- Evang, J. Arild;
- Borota, Olivera Casar;
- Melum, Espen;
- Holm, Ruth;
- Ramm-Pettersen, Jon;
- Bollerslev, Jens;
- Berg, Jens P.
Publication type:
Article
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease.
Published in:
PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0182030
By:
- Landskron, Johannes;
- Kraggerud, Sigrid M.;
- Wik, Elisabeth;
- Dørum, Anne;
- Bjørnslett, Merete;
- Melum, Espen;
- Helland, Øystein;
- Bjørge, Line;
- Lothe, Ragnhild A.;
- Salvesen, Helga B.;
- Taskén, Kjetil
Publication type:
Article
An Interleukin-6 (IL-6) Receptor Polymorphism Affecting Serum Levels of IL-6 Does Not Increase the Risk of Cholangiocarcinoma in Primary Sclerosing Cholangitis.
Published in:
2008
By:
- Melum, Espen;
- Karlsen, Tom H.;
- Bergquist, Annika;
- Schrumpf, Erik;
- Boberg, Kirsten M.
Publication type:
Letter
Lack of association between the chemokine receptor 5 polymorphism CCR5delta32 in rheumatoid arthritis and juvenile idiopathic arthritis.
Published in:
BMC Medical Genetics, 2007, v. 8, p. 33, doi. 10.1186/1471-2350-8-33
By:
- Lindner, Ewald;
- Nordang, Gry B. N.;
- Melum, Espen;
- Flatø, Berit;
- Marit Selvaag, Anne;
- Thorsby, Erik;
- Kvien, Tore K.;
- Förre, Øystein T.;
- Lie, Benedicte A.
Publication type:
Article

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