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- Title
Efficacy of Veno-Venous Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Failure.
- Authors
Jae Jun Lee; Sung Mi Hwang; Jae Houn Ko; Hyoung Soo Kim; Kyung Soon Hong; Hyun Hee Choi; Myung Goo Lee; Chang Youl Lee; Won Ki Lee; Eun Jin Soun; Tae Hun Lee; Jeong Yeol Seo
- Abstract
Purpose: The objective of this study was to evaluate our institutional experience with veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory failure (ARF). Materials and Methods: From January 2007 to August 2013, 31 patients with severe ARF that was due to various causes and refractory to mechanical ventilation with conventional therapy were supported with VV ECMO. A partial pressure of arterial oxygen (PaO2)/inspired fraction of oxygen (FiO2) <100 mm Hg at an FiO2 of 1.0 or a pH <7.25 due to CO2 retention were set as criteria for VV ECMO. Results: Overall, 68% of patients survived among those who had received VV ECMO with a mean PaO2/FiO2 of 56.8 mm Hg. Furthermore, in trauma patients, early use of ECMO had the best outcome with a 94% survival rate. Conclusion: VV ECMO is an excellent, life-saving treatment option in patients suffering from acute and life-threatening respiratory failure due to various causes, especially trauma, and early use of VV ECMO therapy improved outcomes in these patients.
- Subjects
EXTRACORPOREAL membrane oxygenation; ARTIFICIAL respiration; SARS disease; SARS treatment; SURVIVAL analysis (Biometry); HEALTH outcome assessment; PATIENTS
- Publication
Yonsei Medical Journal, 2015, Vol 56, Issue 1, p212
- ISSN
0513-5796
- Publication type
Article
- DOI
10.3349/ymj.2015.56.1.212