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- Title
Smads, TAK1, and Their Common Target ATF-2 Play a Critical Role in Cardiomyocyte Differentiation.
- Authors
Monzen, Koshiro; Hiroi, Yukio; Kudoh, Sumiyo; Akazawa, Hiroshi; Oka, Toru; Takimoto, Eiki; Hayashi, Doubun; Hosoda, Toru; Kawabata, Masahiro; Miyazono, Kohei; Ishii, Shunsuke; Yazaki, Yoshio; Nagai, Ryozo; Komuro, Issei
- Abstract
Examines role of transcription factors in cardiomyocyte differentiation of P19CL6, a clonal derivative of murine P19 cells. Bone morphogenetic proteins; Detection of phosphorylated ATF-2 protein; Examination of differentiation efficiency; Expression of cardiac-specific genes; Activation of promoters.
- Subjects
TRANSCRIPTION factors; HEART cells; GENETIC regulation; RATS; CYTOLOGY
- Publication
Journal of Cell Biology, 2001, Vol 153, Issue 4, p687
- ISSN
0021-9525
- Publication type
Article
- DOI
10.1083/jcb.153.4.687