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- Title
Antiproliferative Activity of Root Extract from Gentian Plant (Gentiana triflora) on Cultured and Implanted Tumor Cells.
- Authors
Matsukawa, Kazushige; Ogata, Mika; Hikage, Takashi; Minami, Hiroyuki; Shim0tai, Yoshitaka; Saitoh, Yasushi; Yamashita, Tetsuro; Ouchi, Atsushi; Tsutsumi, Reiko; Fujioka, Tomoaki; Tsutsumi, Ken-ichi
- Abstract
The article discusses the results of a study which examined the pharmacological activity of the gentian root on cultured and implanted tumor cells. Root extract from Gentiana triflora triggered death of tumor cells. Treatment of cultured cells by the gentian root resulted in the appearance of shrunken, fragmented or condensed cell and nuclear morphologies, and in chromosomal DNA degradation.
- Subjects
PLANT roots; GENTIANA; CANCER cells; CELL culture; CELL death; DNA
- Publication
Bioscience, Biotechnology & Biochemistry, 2006, Vol 70, Issue 4, p1046
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1271/bbb.70.1046