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- Title
Determinants of quality of life among long-term breast cancer survivors.
- Authors
Chu, Wai-on; Dialla, Pegdwende; Roignot, Patrick; Bone-Lepinoy, Marie-Christine; Poillot, Marie-Laure; Coutant, Charles; Arveux, Patrick; Dabakuyo-Yonli, Tienhan; Dialla, Pegdwende Olivia; Dabakuyo-Yonli, Tienhan Sandrine
- Abstract
<bold>Purpose: </bold>To identify the impact of clinical and socio-economic determinants on quality of life (QoL) among breast cancer (BC) survivors 5 years after diagnosis.<bold>Methods: </bold>A cross-sectional survey was conducted in women diagnosed in 2007 for primary invasive non-metastatic BC and identified through the Côte d'Or BC registry. QoL was assessed with the Medical Outcomes Study 12-item Short Form Health Survey (SF-12), the European Organization for Research and Treatment of Cancer Quality of Life (EORTC-QLQ-C30) and the breast cancer (EORTC-QLQ-BR23) questionnaires. Social support was assessed with Sarason's social support questionnaire, and deprivation was assessed by the EPICES questionnaire. Clinical variables were collected through the registry database. Determinants of QoL were identified using multivariable mixed model analysis for each SF-12 dimension. A sensitivity analysis was conducted with multiple imputations on missing data.<bold>Results: </bold>Overall, 188 patients on 319 patients (59 %) invited to participate to the survey completed the questionnaires. Five years after breast cancer diagnosis, the disease stages at diagnosis, as well as the treatment received, were not determinants of QoL. Only the age at diagnosis and comorbidities were found to be determinants of QoL.<bold>Conclusions: </bold>Five years after BC diagnosis, disease severity and the treatment received did not affect QoL.
- Subjects
BREAST cancer patients; QUALITY of life; HEALTH surveys; MULTIVARIABLE testing; DIAGNOSIS; BREAST tumors; QUESTIONNAIRES; SICKNESS Impact Profile; CROSS-sectional method; CANCER &; psychology
- Publication
Quality of Life Research, 2016, Vol 25, Issue 8, p1981
- ISSN
0962-9343
- Publication type
journal article
- DOI
10.1007/s11136-016-1248-z