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- Title
Factors associated with health-related quality of life among hemodialysis patients in the DOPPS.
- Authors
Lopes, Antonio; Bragg-Gresham, Jennifer; Goodkin, David; Fukuhara, Shunichi; Mapes, Donna; Young, Eric; Gillespie, Brenda; Akizawa, Tadao; Greenwood, Roger; Andreucci, Vittorio; Akiba, Takashi; Held, Philip; Port, Friedrich; Lopes, Antonio Alberto; Bragg-Gresham, Jennifer L; Goodkin, David A; Mapes, Donna L; Young, Eric W; Gillespie, Brenda W; Greenwood, Roger N
- Abstract
<bold>Objective: </bold>To identify modifiable factors associated with health-related quality of life (HRQOL) among chronic hemodialysis patients.<bold>Methods: </bold>Analysis of baseline data of 9,526 hemodialysis patients from seven countries enrolled in phase I of the Dialysis Outcomes and Practice Patterns Study (DOPPS). Using the Kidney Disease Quality of Life Short Form (KDQOL-SF(TM)), we determined scores for 8 generic scale summaries derived from these scales, i.e., the physical component summary [PCS] and mental component summary [MCS], and 11 kidney disease- targeted scales. Regression models were used to adjust for differences in comorbidities and sociodemographic and treatment factors. The Benjamini-Hochberg procedure was used to correct P-values for multiple comparisons.<bold>Results: </bold>Unemployment and psychiatric disease were independently and significantly associated with lower scores for all generic and several kidney disease-targeted HRQOL measures. Several other comorbidities, lower educational level, lower income, and hypoalbuminemia were also independently and significantly associated with lower scores of PCS and/or MCS and several generic and kidney disease-targeted scales. Hemodialysis by catheter was associated with significantly lower PCS scores, partially explained by the correlation with covariates.<bold>Conclusion: </bold>Associations of poorer HRQOL with preventable or controllable factors support a greater focus on psychosocial and medical interventions to improve the well-being of hemodialysis patients.
- Subjects
QUALITY of life; HEALTH; HEMODIALYSIS patients; CHRONIC diseases; KIDNEY disease treatments
- Publication
Quality of Life Research, 2007, Vol 16, Issue 4, p545
- ISSN
0962-9343
- Publication type
journal article
- DOI
10.1007/s11136-006-9143-7