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- Title
Improvement in patient‐reported "taste" and association with smell in dupilumab‐treated patients with severe chronic rhinosinusitis with nasal polyps from the SINUS‐24 and SINUS‐52 trials.
- Authors
Peters, Anju T.; Soler, Zachary M.; Kern, Robert C.; Heffler, Enrico; Maspero, Jorge F.; Crampette, Louis; Fujieda, Shigeharu; Lane, Andrew P.; Zhang, Haixin; Nash, Scott; Khan, Asif H.; Siddiqui, Shahid; Jacob‐Nara, Juby A.; Rowe, Paul; Deniz, Yamo
- Abstract
In conclusion, our analysis shows that in patients with severe CRSwNP, dupilumab treatment improved patient-reported "taste" versus placebo. Sense of smell was measured using the loss-of-smell score (LoS) - reported daily by patients on a scale of 0-3, similar to how patient-reported taste was measured - UPSIT and the SNOT-22 smell/taste item. Improvement in patient-reported "taste" and association with smell in dupilumab-treated patients with severe chronic rhinosinusitis with nasal polyps from the SINUS-24 and SINUS-52 trials Post-hoc analysis showed dupilumab significantly improves patient-reported "taste" versus placebo in patients with severe CRSwNP.
- Subjects
SMELL disorders; NASAL polyps; SMELL; SINUSITIS; OLFACTOMETRY
- Publication
Clinical & Experimental Allergy, 2022, Vol 52, Issue 9, p1105
- ISSN
0954-7894
- Publication type
Article
- DOI
10.1111/cea.14194