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- Title
Evidence for corticotropin-releasing factor regulation of serotonin in the lateral septum during acute swim stress: adaptation produced by repeated swimming.
- Authors
Price, Michelle L.; Kirby, Lynn G.; Valentino, Rita J.; Lucki, Irwin
- Abstract
Presents a study to test the hypothesis that endogenous Corticotropin-releasing factor (CRF) mediates the reduction of 5-HT levels in the lateral septum evoked by swim stress and is involved in the adaptation that occurs with repeated swim stress. Methods; Results; Conclusion that endogenous CRF modulates 5-HT transmission during acute environmental stress and is also integral to adaptation of the 5-HT response produced by repeated stress.
- Subjects
ADRENOCORTICOTROPIC hormone; PHYSIOLOGICAL stress; SEPTUM (Brain); ANTIDEPRESSANTS
- Publication
Psychopharmacology, 2002, Vol 162, Issue 4, p406
- ISSN
0033-3158
- Publication type
Article
- DOI
10.1007/s00213-002-1114-2