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- Title
Malignant Lymphoma of the Transverse Colon Associated with Macroglobulinemia.
- Authors
Yasui, Ouki; Tukamoto, Fumihito; Sasaki, Noriaki; Saito, Takako; Yagisawa, Hitoshi; Uno, Atsushi; Nanjo, Hirosi
- Abstract
We present an unusual case of a malignant lymphoma of the transverse colon associated with macroglobulinemia. A 73-yr-old man was incidentally discovered to have high serum γ-globulin on a regular check-up. Serum immunoquantitation revealed an IgM level of 3490 mg/dl. Kappa-type Bence-Jones protein was positive in the urine. Immunoelectrophoresis identified the abnormal protein as IgM-kappa. After hospitalization an abdominal tumor was detected with barium and CT, identified as a tumor of the transverse colon. Partial resection of the transverse colon was carried out. Histopathologically the tumor were confirmed as small lymphocytic non-Hodgkin lymphoma of B-cell origin, based on the Working Formulation. According to flowcytometric analysis, the tumor cells were positive for IgM-kappa. The lymphoma cells produced monoclonal IgM, giving rise to macroglobulinemia.
- Subjects
LYMPHOMAS; URINE; IMMUNOELECTROPHORESIS; BARIUM; HISTOPATHOLOGY; PROTEINS
- Publication
American Journal of Gastroenterology (Springer Nature), 1997, Vol 92, Issue 12, p2299
- ISSN
0002-9270
- Publication type
Article