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Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.
Published in:
2018
By:
- Shahin, Mohamed H.;
- Gong, Yan;
- Frye, Reginald F.;
- Rotroff, Daniel M.;
- Beitelshees, Amber L.;
- Baillie, Rebecca A.;
- Chapman, Arlene B.;
- Gums, John G.;
- Turner, Stephen T.;
- Boerwinkle, Eric;
- Motsinger‐Reif, Alison;
- Fiehn, Oliver;
- Cooper‐DeHoff, Rhonda M.;
- Han, Xianlin;
- Kaddurah‐Daouk, Rima;
- Johnson, Julie A.;
- Motsinger-Reif, Alison;
- Cooper-DeHoff, Rhonda M;
- Kaddurah-Daouk, Rima
Publication type:
journal article
Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study.
Published in:
2015
By:
- Ellero ‐ Simatos, Sandrine;
- Beitelshees, Amber L.;
- Lewis, Joshua P.;
- Yerges ‐ Armstrong, Laura M.;
- Georgiades, Anastasia;
- Dane, Adrie;
- Harms, Amy C.;
- Strassburg, Katrin;
- Guled, Faisa;
- Hendriks, Margriet M. W. B.;
- Horenstein, Richard B.;
- Shuldiner, Alan R.;
- Hankemeier, Thomas;
- Kaddurah ‐ Daouk, Rima;
- Ellero-Simatos, Sandrine;
- Yerges-Armstrong, Laura M;
- Kaddurah-Daouk, Rima;
- Pharmacometabolomics Research Network
Publication type:
journal article
α-synuclein overexpression and the microbiome shape the gut and brain metabolome in mice.
Published in:
NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00816-w
By:
- Morais, Livia H.;
- Boktor, Joseph C.;
- MahmoudianDehkordi, Siamak;
- Kaddurah-Daouk, Rima;
- Mazmanian, Sarkis K.
Publication type:
Article
3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia.
Published in:
International Journal of Neuropsychopharmacology, 2011, v. 14, n. 6, p. 756, doi. 10.1017/S1461145710001689
By:
- Condray, Ruth;
- Dougherty, George G.;
- Keshavan, Matcheri S.;
- Reddy, Ravinder D.;
- Haas, Gretchen L.;
- Montrose, Debra M.;
- Matson, Wayne R.;
- McEvoy, Joseph;
- Kaddurah-Daouk, Rima;
- Yao, Jeffrey K.
Publication type:
Article
Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99845-1
By:
- Brydges, Christopher R.;
- Fiehn, Oliver;
- Mayberg, Helen S.;
- Schreiber, Henry;
- Dehkordi, Siamak Mahmoudian;
- Bhattacharyya, Sudeepa;
- Cha, Jungho;
- Choi, Ki Sueng;
- Craighead, W. Edward;
- Krishnan, Ranga R.;
- Rush, A. John;
- Dunlop, Boadie W.;
- Kaddurah-Daouk, Rima;
- the Mood Disorders Precision Medicine Consortium;
- Penninx, Brenda;
- Binder, Elizabeth;
- Kastenmüller, Gabi;
- Arnold, Matthias;
- Nevado-Helgado, Alejo;
- Blach, Colette
Publication type:
Article
Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98640-2
By:
- Borkowski, Kamil;
- Taha, Ameer Y.;
- Pedersen, Theresa L.;
- De Jager, Philip L.;
- Bennett, David A.;
- Arnold, Matthias;
- Kaddurah-Daouk, Rima;
- Newman, John W.
Publication type:
Article
Multi-Omics Characterization of Early- and Adult-Onset Major Depressive Disorder.
Published in:
Journal of Personalized Medicine, 2022, v. 12, n. 3, p. 412, doi. 10.3390/jpm12030412
By:
- Grant, Caroline W.;
- Barreto, Erin F.;
- Kumar, Rakesh;
- Kaddurah-Daouk, Rima;
- Skime, Michelle;
- Mayes, Taryn;
- Carmody, Thomas;
- Biernacka, Joanna;
- Wang, Liewei;
- Weinshilboum, Richard;
- Trivedi, Madhukar H.;
- Bobo, William V.;
- Croarkin, Paul E.;
- Athreya, Arjun P.
Publication type:
Article
Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.984383
By:
- Grant, Caroline W.;
- Wilton, Angelina R.;
- Kaddurah-Daouk, Rima;
- Skime, Michelle;
- Biernacka, Joanna;
- Mayes, Taryn;
- Carmody, Thomas;
- Wang, Liewei;
- Lazaridis, Konstantinos;
- Weinshilboum, Richard;
- Bobo, William V.;
- Trivedi, Madhukar H.;
- Croarkin, Paul E.;
- Athreya, Arjun P.
Publication type:
Article
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
Published in:
Nature Medicine, 1999, v. 5, n. 3, p. 347, doi. 10.1038/6568
By:
- Klivenyi, Peter;
- Ferrante, Robert J.;
- Matthews, Russell T.;
- Bogdanov, Mikhail B.;
- Klein, Autumn M.;
- Andreassen, Ole A.;
- Mueller, Gerald;
- Wermer, Marieke;
- Kaddurah-Daouk, Rima;
- Beal, M. Flint
Publication type:
Article
Symposium: What Does the Microbiome Tell Us about Prevention and Treatment of AD/ADRD?
Published in:
Journal of Neuroscience, 2024, v. 44, n. 41, p. 1, doi. 10.1523/JNEUROSCI.1295-24.2024
By:
- Capocchi, Joia K.;
- Figueroa-Romero, Claudia;
- Dunham, Sage J. B.;
- Faraci, Gina;
- Rothman, Jason A.;
- Whiteson, Katrine L.;
- Seo, Dong-oh;
- Holtzman, David M.;
- Grabrucker, Stefanie;
- Nolan, Yvonne M.;
- Kaddurah-Daouk, Rima;
- Jett, David A.
Publication type:
Article
Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 3987, doi. 10.1002/alz.13851
By:
- Pandey, Ravi S.;
- Arnold, Mattias;
- Batra, Richa;
- Krumsiek, Jan;
- Kotredes, Kevin P.;
- Garceau, Dylan;
- Williams, Harriet;
- Sasner, Michael;
- Howell, Gareth R.;
- Kaddurah‐Daouk, Rima;
- Carter, Gregory W.
Publication type:
Article
Sexual dimorphisms in longitudinal associations of the blood lipidome with cognitive decline in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082967
By:
- Marella, Bharadwaj;
- Weinisch, Patrick;
- Huynh, Kevin;
- Risacher, Shannon L;
- Wilhelm, Mathias;
- Kaddurah‐Daouk, Rima F.;
- Meikle, Peter J;
- Kastenmuller, Gabi;
- Arnold, Matthias
Publication type:
Article
A modified Mediterranean‐ketogenic diet favorably modulates the metabolic profiles of mild cognitively impaired individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079848
By:
- Batra, Richa;
- Huynh, Kevin;
- Schweickart, Annalise;
- Neth, Bryan J.;
- Arnold, Matthias;
- Kastenmuller, Gabi;
- Meikle, Peter J;
- Craft, Suzanne;
- Krumsiek, Jan;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
Gut microbiome‐related metabolites in plasma are associated with general cognition.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078299
By:
- Kastenmuller, Gabi;
- Wu, Tong;
- Arnold, Matthias;
- Hankemeier, Thomas;
- Ghanbari, Mohsen;
- Uitterlinden, André G.;
- Kraaij, Robert;
- Van Duijn, Cornelia M;
- Kaddurah‐Daouk, Rima F.;
- Ikram, M. Arfan
Publication type:
Article
Bile acids inform about a sex‐specific resilience phenotype against Alzheimer's disease implicating a role for the gut microbiome and the exposome.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078297
By:
- Kristal, Bruce;
- Sniatynski, Matthew J;
- MahmoudianDehkordi, Siamak;
- Kastenmuller, Gabi;
- Nho, Kwangsik;
- Arnold, Matthias;
- Borkowski, Kamil;
- Jia, Wei;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
Gut microbiome moderates the association between metabolic syndrome and the cerebrospinal fluid concentration of YKL‐40 in a cognitively unimpaired cohort.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077952
By:
- Peter, Darby;
- Heston, Margo B.;
- Ennis, Gilda E.;
- Knight, Rob;
- Kaddurah‐Daouk, Rima F.;
- Johnson, Sterling C;
- Asthana, Sanjay;
- Carlsson, Cynthia M.;
- Chin, Nathaniel A.;
- Kollmorgen, Gwendlyn;
- Carboni, Margherita;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Ulland, Tyler K.;
- Rey, Federico E.;
- Bendlin, Barbara B
Publication type:
Article
Correlational analysis of plasma metabolome and brain imaging in a humanized APOE mouse model.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080468
By:
- Bhattrai, Avnish;
- McLean, John W.;
- Simmons, Hannah;
- Raikes, Adam C.;
- Wiegand, Jean‐Paul L.;
- Kaddurah‐Daouk, Rima F.;
- Brinton, Roberta Diaz
Publication type:
Article
Plasma metabolomic profiles of aged, humanized APOE mice and behavioral correlates.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080101
By:
- McLean, John W.;
- Bhattrai, Avnish;
- Simmons, Hannah;
- Wiegand, Jean‐Paul L.;
- Raikes, Adam C.;
- Kaddurah‐Daouk, Rima F.;
- Brinton, Roberta Diaz
Publication type:
Article
Preclinical Alzheimer's disease is associated with distinct gut microbial metagenomic profiles.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073847
By:
- Kang, Jea Woo;
- Heston, Margo B.;
- Deming, Yuetiva;
- González, Antonio;
- Ulland, Tyler K.;
- Johnson, Sterling C;
- Asthana, Sanjay;
- Carlsson, Cynthia M.;
- Chin, Nathaniel A.;
- Grover, Ethan;
- Vemuganti, Vaibhav BV;
- Kollmorgen, Gwendlyn;
- Carboni, Margherita;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Knight, Rob;
- Kaddurah‐Daouk, Rima F.;
- Rey, Federico E.;
- Bendlin, Barbara B
Publication type:
Article
Gut microbial composition mediates the relationship between intestinal inflammation and amyloid burden before cognitive decline.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078994
By:
- Heston, Margo B.;
- Hong, Qilin;
- González, Antonio;
- Betthauser, Tobey J;
- Chin, Nathaniel A.;
- Hanslik, Kendra L.;
- Zarbock, Katie R;
- Kerby, Robert L.;
- Asthana, Sanjay;
- Johnson, Sterling C;
- Knight, Rob;
- Kaddurah‐Daouk, Rima F.;
- Tang, ZhengZheng;
- Ulland, Tyler K.;
- Rey, Federico E.;
- Bendlin, Barbara B
Publication type:
Article
Pseudo‐temporal models of Alzheimer's Disease progression across brain‐derived transcriptomics, proteomics, and metabolomics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080320
By:
- Heath, Laura M;
- Batra, Richa;
- Cary, Gregory A.;
- Wiley, Jesse C;
- Poehlman, William L.;
- Linden, Abby Vander;
- Krumsiek, Jan;
- Arnold, Matthias;
- Kaddurah‐Daouk, Rima F.;
- Carter, Gregory W;
- Greenwood, Anna K
Publication type:
Article
Gut microbial families associate with brain volume in cognitively unimpaired aging adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077917
By:
- Ibrahim, Muhaison H;
- Heston, Margo B.;
- Kang, Jea Woo;
- Ennis, Gilda E.;
- Harding, Sandra;
- González, Antonio;
- Johnson, Sterling C;
- Asthana, Sanjay;
- Knight, Rob;
- Kaddurah‐Daouk, Rima F.;
- Rey, Federico E.;
- Bendlin, Barbara B
Publication type:
Article
An Integrative Multi‐Omics Approach Reveals Molecular Signatures Associated with Age and High‐Fat Diet in Mouse Models of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077260
By:
- Pandey, Ravi S;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Haber, Annat;
- MahmoudianDehkordi, Siamak;
- Shantaraman, Anantharaman;
- Duong, Duc M.;
- Seyfried, Nicholas T;
- Kaddurah‐Daouk, Rima F.;
- Sasner, Michael;
- Howell, Gareth R;
- Oblak, Adrian L;
- Lamb, Bruce T;
- Carter, Gregory W
Publication type:
Article
In silico prioritiziation of drug repositioning candidates for Alzheimer's disease using signature search meta‐analysis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076844
By:
- Bellur, Orhan;
- Kastenmuller, Gabi;
- Requena, Francisco;
- Kaddurah‐Daouk, Rima F.;
- Krumsiek, Jan;
- Arnold, Matthias
Publication type:
Article
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072776
By:
- Arnold, Matthias;
- Buyukozkan, Mustafa;
- Doraiswamy, P. Murali;
- Wu, Tong;
- Nho, Kwangsik;
- Gudnason, Vilmundur;
- Launer, Lenore J J.;
- Wang‐Sattler, Rui;
- Adamski, Jerzy;
- De Jager, Philip L;
- Ertekin‐Taner, Nilufer;
- Bennett, David A. A;
- Saykin, Andrew J.;
- Peters, Annette;
- Suhre, Karsten;
- Kaddurah‐Daouk, Rima F.;
- Kastenmuller, Gabi;
- Krumsiek, Jan
Publication type:
Article
Gut microbial composition mediates the relationship between intestinal inflammation and amyloid burden before cognitive decline.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081862
By:
- Heston, Margo B.;
- Hong, Qilin;
- González, Antonio;
- Betthauser, Tobey J;
- Chin, Nathaniel A.;
- Hanslik, Kendra L.;
- Zarbock, Katie R;
- Kerby, Robert L.;
- Asthana, Sanjay;
- Johnson, Sterling C;
- Knight, Rob;
- Kaddurah‐Daouk, Rima F.;
- Tang, ZhengZheng;
- Ulland, Tyler K.;
- Rey, Federico E.;
- Bendlin, Barbara B
Publication type:
Article
Pseudo‐temporal models of Alzheimer's Disease progression across brain‐derived transcriptomics, proteomics, and metabolomics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080320
By:
- Heath, Laura M;
- Batra, Richa;
- Cary, Gregory A.;
- Wiley, Jesse C;
- Poehlman, William L.;
- Linden, Abby Vander;
- Krumsiek, Jan;
- Arnold, Matthias;
- Kaddurah‐Daouk, Rima F.;
- Carter, Gregory W;
- Greenwood, Anna K
Publication type:
Article
Gut microbial families associate with brain volume in cognitively unimpaired aging adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077917
By:
- Ibrahim, Muhaison H;
- Heston, Margo B.;
- Kang, Jea Woo;
- Ennis, Gilda E.;
- Harding, Sandra;
- González, Antonio;
- Johnson, Sterling C;
- Asthana, Sanjay;
- Knight, Rob;
- Kaddurah‐Daouk, Rima F.;
- Rey, Federico E.;
- Bendlin, Barbara B
Publication type:
Article
An Integrative Multi‐Omics Approach Reveals Molecular Signatures Associated with Age and High‐Fat Diet in Mouse Models of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077260
By:
- Pandey, Ravi S;
- Kotredes, Kevin P;
- Garceau, Dylan;
- Haber, Annat;
- MahmoudianDehkordi, Siamak;
- Shantaraman, Anantharaman;
- Duong, Duc M.;
- Seyfried, Nicholas T;
- Kaddurah‐Daouk, Rima F.;
- Sasner, Michael;
- Howell, Gareth R;
- Oblak, Adrian L;
- Lamb, Bruce T;
- Carter, Gregory W
Publication type:
Article
In silico prioritiziation of drug repositioning candidates for Alzheimer's disease using signature search meta‐analysis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076844
By:
- Bellur, Orhan;
- Kastenmuller, Gabi;
- Requena, Francisco;
- Kaddurah‐Daouk, Rima F.;
- Krumsiek, Jan;
- Arnold, Matthias
Publication type:
Article
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072776
By:
- Arnold, Matthias;
- Buyukozkan, Mustafa;
- Doraiswamy, P. Murali;
- Wu, Tong;
- Nho, Kwangsik;
- Gudnason, Vilmundur;
- Launer, Lenore J J.;
- Wang‐Sattler, Rui;
- Adamski, Jerzy;
- De Jager, Philip L;
- Ertekin‐Taner, Nilufer;
- Bennett, David A. A;
- Saykin, Andrew J.;
- Peters, Annette;
- Suhre, Karsten;
- Kaddurah‐Daouk, Rima F.;
- Kastenmuller, Gabi;
- Krumsiek, Jan
Publication type:
Article
Effects of a ketogenic and low‐fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 11, p. 4805, doi. 10.1002/alz.13007
By:
- Dilmore, Amanda Hazel;
- Martino, Cameron;
- Neth, Bryan J.;
- West, Kiana A.;
- Zemlin, Jasmine;
- Rahman, Gibraan;
- Panitchpakdi, Morgan;
- Meehan, Michael J.;
- Weldon, Kelly C.;
- Blach, Colette;
- Schimmel, Leyla;
- Kaddurah‐Daouk, Rima;
- Dorrestein, Pieter C.;
- Knight, Rob;
- Craft, Suzanne
Publication type:
Article
Evolution of circulating metabolites through lifespan according to gender and APOE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067134
By:
- Bonnechère, Bruno;
- Liu, Jun;
- Amin, Najaf;
- Kaddurah‐Daouk, Rima F.;
- Van Duijn, Cornelia M
Publication type:
Article
Multi‐omics characterization of brain‐based pseudotime estimates for Alzheimer's disease progression.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065437
By:
- Wörheide, Maria A.;
- Batra, Richa;
- Krumsiek, Jan;
- Kaddurah‐Daouk, Rima F.;
- Kastenmuller, Gabi;
- Arnold, Matthias
Publication type:
Article
Predictive metabolic networks reveal sex‐ and APOE genotype‐specific metabolic signatures and drivers for precision medicine in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 2, p. 518, doi. 10.1002/alz.12675
By:
- Chang, Rui;
- Trushina, Eugenia;
- Zhu, Kuixi;
- Zaidi, Syed Shujaat Ali;
- Lau, Branden M.;
- Kueider‐Paisley, Alexandra;
- Moein, Sara;
- He, Qianying;
- Alamprese, Melissa L.;
- Vagnerova, Barbora;
- Tang, Andrew;
- Vijayan, Ramachandran;
- Liu, Yanyun;
- Saykin, Andrew J.;
- Brinton, Roberta D.;
- Kaddurah‐Daouk, Rima
Publication type:
Article
The landscape of metabolic brain alterations in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 3, p. 980, doi. 10.1002/alz.12714
By:
- Batra, Richa;
- Arnold, Matthias;
- Wörheide, Maria A.;
- Allen, Mariet;
- Wang, Xue;
- Blach, Colette;
- Levey, Allan I.;
- Seyfried, Nicholas T.;
- Ertekin‐Taner, Nilüfer;
- Bennett, David A.;
- Kastenmüller, Gabi;
- Kaddurah‐Daouk, Rima F.;
- Krumsiek, Jan
Publication type:
Article
Bacteroides genus is associated with lower executive function in cognitively unimpaired participants.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 1, doi. 10.1002/alz.069291
By:
- Forst, Allison A;
- Heston, Margo B.;
- González, Antonio;
- Chin, Nathaniel A.;
- Przybelski, Robert J;
- Johnson, Sterling C.;
- Asthana, Sanjay;
- Knight, Rob;
- Kaddurah‐Daouk, Rima;
- Rey, Federico E.;
- Bendlin, Barbara B.
Publication type:
Article
Associations between gut microbial families and brain myelin in a human cohort.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069400
By:
- Yang, Kao Lee;
- Heston, Margo B.;
- Kohli, Akshay;
- Kecskemeti, Steven R;
- González, Antonio;
- Knight, Rob;
- Kaddurah‐Daouk, Rima;
- Rey, Federico E.;
- Bendlin, Barbara B.
Publication type:
Article
Novel circling SWAT for deep learning based diagnostic classification of Alzheimer's disease: Application to metabolome data.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069310
By:
- Jo, Taeho;
- Kim, Junpyo;
- Bice, Paula;
- Huynh, Kevin;
- Wang, Tingting;
- Meikle, Peter J;
- Kaddurah‐Daouk, Rima;
- Nho, Kwangsik;
- Saykin, Andrew J.
Publication type:
Article
Interactions between brain and bile acid ratio profiles predict baseline cognitive status.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067272
By:
- Labus, Jennifer S;
- Liu, Cathy;
- Blach, Colette;
- Arnold, Matthias;
- Kaddurah‐Daouk, Rima F.;
- Mayer, Emeran A
Publication type:
Article
Brain region‐specific metabolic signatures of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067879
By:
- Batra, Richa;
- Krumsiek, Jan;
- Wang, Xue;
- Allen, Mariet;
- Wörheide, Maria A.;
- Blach, Colette;
- Bennett, David A;
- Kastenmüller, Gabi;
- Arnold, Matthias;
- Ertekin‐Taner, Nilufer;
- Kaddurah‐Daouk, Rima
Publication type:
Article
Metabolomics profiling reveals distinct signatures in the serum and brain metabolomes in mouse models of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.064137
By:
- Pandey, Ravi S;
- Hoffmann, Brian;
- Arnold, Matthias;
- Greene, Andrew S;
- Kaddurah‐Daouk, Rima F.;
- Carter, Gregory W
Publication type:
Article
Mapping the human brain metabolome and influences of gut microbiome.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056270
By:
- Batra, Richa;
- Heinken, Almut;
- Karu, Naama;
- Arnold, Matthias;
- Kastenmüller, Gabi;
- Hankemeier, Thomas;
- Bennett, David A.;
- Knight, Rob;
- Krumsiek, Jan;
- Thiele, Ines;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
Profiling the metabolome of patients with dementia in the UK Biobank.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056147
By:
- Liu, Jun;
- Amin, Najaf;
- Arnold, Matthias;
- Nho, Kwangsik;
- Saykin, Andrew J.;
- Newby, Danielle;
- Winchester, Laura M.;
- Nevado‐Holgado, Alejo J.;
- Kastenmüller, Gabi;
- Kaddurah‐Daouk, Rima F.;
- Van Duijn, Cornelia M.
Publication type:
Article
Transcriptomics, metabolomics, lipidomics, metabolic flux and mGWAS analyses of sphingolipid pathway highlights novel drugs for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056152
By:
- Baloni, Priyanka;
- Arnold, Matthias;
- Moreno, Herman;
- Nho, Kwangsik;
- Kastenmüller, Gabi;
- Suhre, Karsten;
- Buitrago, Luna;
- Louie, Gregory;
- Kueider‐Paisley, Alexandra;
- Saykin, Andrew J.;
- Ekroos, Kim;
- Meikle, Peter J.;
- Huynh, Kevin;
- Funk, Cory C.;
- Hood, Leroy;
- Price, Nathan D.;
- Baillie, Rebecca;
- Han, Xianlin;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
Gut microbiome‐related metabolites in plasma are associated with general cognition.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056142
By:
- Ahmad, Shahzad;
- Arnold, Matthias;
- Hankemeier, Thomas;
- Ghanbari, Mohsen;
- Uitterlinden, André G.;
- Kraaij, Robert;
- Van Duijn, Cornelia M.;
- Kaddurah‐Daouk, Rima F.;
- Kastenmüller, Gabi;
- Ikram, M. Arfan
Publication type:
Article
A proof of concept study towards multi‐omics‐based computational drug repositioning in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056673
By:
- Wörheide, Maria A.;
- Krumsiek, Jan;
- Kastenmüller, Gabi;
- Kaddurah‐Daouk, Rima F.;
- Arnold, Matthias
Publication type:
Article
Investigating the importance of acylcarnitines in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056647
By:
- Baloni, Priyanka;
- Nho, Kwangsik;
- Arnold, Matthias;
- Louie, Gregory;
- Kueider‐Paisley, Alexandra;
- Saykin, Andrew J.;
- Ekroos, Kim;
- Funk, Cory;
- Hood, Leroy;
- Price, Nathan D;
- Baillie, Rebecca;
- Kastenmüller, Gabi;
- Han, Xianlin;
- Kaddurah‐Daouk, Rima F.
Publication type:
Article
The metabolic landscape of brain alterations in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054793
By:
- Batra, Richa;
- Arnold, Matthias;
- Kastenmüller, Gabi;
- Allen, Mariet;
- Wang, Xue;
- Bennett, David A.;
- Ertekin‐Taner, Nilüfer;
- Kaddurah‐Daouk, Rima F.;
- Krumsiek, Jan
Publication type:
Article
Integrative metabolomics‐genomics approach reveals that pathways related to the metabolism of acylcarnitines and amines are new potential targets of Alzheimer's disease: Genome‐metabolome‐phenome: Towards an integrated molecular atlas for Alzheimer's disease
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045610
By:
- Horgusluoglu‐Moloch, Emrin;
- Wang, Minghui;
- Arnold, Matthias;
- Krumsiek, Jan;
- Galindo‐Prieto, Beatriz;
- Kastenmüller, Gabi;
- Han, Xianlin;
- Baillie, Rebecca;
- Nho, Kwangsik;
- Saykin, Andrew J.;
- Kaddurah‐Daouk, Rima F.;
- Zhang, Bin
Publication type:
Article

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