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- Title
US-guided transcutaneous tru-cut biopsy of laryngo-hypopharyngeal lesions.
- Authors
Preda L; De Fiori E; Rampinelli C; Ansarin M; Petralia G; Maffini F; Alterio D; Bonello L; Chiesa F; Bellomi M; Preda, Lorenzo; De Fiori, Elvio; Rampinelli, Cristiano; Ansarin, Mohssen; Petralia, Giuseppe; Maffini, Fausto; Alterio, Daniela; Bonello, Luke; Chiesa, Fausto; Bellomi, Massimo
- Abstract
<bold>Objective: </bold>To evaluate the feasibility and performance of ultrasound-guided transcutaneous tru-cut biopsy (USGTCB) in selected patients (with stenosis of airways or difficult intubation or contraindication to general anaesthesia) with untreated or previously treated suspicious laryngo-hypopharyngeal masses.<bold>Methods: </bold>Biopsies were performed with a free-hand technique by a single radiologist. Thirty-six USGTCBs were scheduled in 34 patients (24 males, 10 females; age range 47-95 years). Two USGTCBs were not performed, as lesions were not detectable: therefore, 16 USGTCBs were performed for an untreated mass suspicious for malignancy and 18 were performed for a mass suspicious for recurrence after radiotherapy alone, or associated with endoscopic laser surgery or chemotherapy.<bold>Results: </bold>USGTCB diagnosed 25 squamous cell carcinomas (73.5%) and nine benign lesions (26.5%); no false positives and two false negatives were reported, both in patients previously treated with radiotherapy. The sensitivity, specificity, positive and negative predictive value of the technique was 92.5%, 100%, 100% and 77.7% respectively, with no major complications.<bold>Conclusion: </bold>Although biopsy under microlaryngoscopy remains the "gold-standard" technique, USGTCB is feasible, carries the advantages of avoiding general anaesthesia, is suitable for outpatients and is cost-effective. If applied to selected patients, it could be considered for the histological diagnosis of both primary and recurrent laryngo-hypopharyngeal masses.
- Publication
European Radiology, 2010, Vol 20, Issue 6, p1450
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-009-1682-1