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- Title
Elution and antibacterial activity of meropenem from implanted acrylic bone cement.
- Authors
Solomon, Anthony W.; Stott, Philip M.; Duffy, Kim; Kumar, P. G. Anil; Holliman, Richard E.; Bridle, Simon H.
- Abstract
The article describes a case involving the use of meropenem-loaded polymethylmethacrylate (PMMA) bone cement in human prosthetic joint infection in a 66-year-old woman. The patient developed a wound haematoma after undergoing prosthetic hip revision, which was washed out when it started to discharge. Meropenem was mixed with sterile orthopaedic bone cement that contained gentamicin and clindamycin, which was used to fix the patient's replacement acetabular prosthesis.
- Subjects
BONE cements; ARTIFICIAL joints; GENTAMICIN; CLINDAMYCIN; POLYMETHYLMETHACRYLATE; INFECTION; HEMATOMA; OLDER women
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2010, Vol 65, Issue 8, p1834
- ISSN
0305-7453
- Publication type
Article
- DOI
10.1093/jac/dkq196