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- Title
How Much Should We Eat? The Association Between Energy Intake and Mortality in a 36-Year Follow-Up Study of Japanese-American Men.
- Authors
Willcox, Bradley J.; Yano, Katsuhiko; Chen, Randi; Willcox, D. Craig; Rodriguez, Beatriz L.; Masaki, Kamal H.; Donlon, Timothy; Tanaka, Brandi; Curb, J. David
- Abstract
Energy restriction extends life span and lowers mortality from age-related diseases in many species, but the effects in humans are unknown. We prospectively examined this relationship in a large epidemiological study of Japanese-American men. We followed 1915 healthy nonsmokers, aged 45-68 years at study onset, for 36 years. Twenty-four-hour recall of diet was recorded at baseline, and follow-up was for all-cause mortality. After adjustment for age and other confounders, there was a trend toward lower mortality in the second quintile of energy intake, suggesting that men who consumed 15% below the group mean were at the lowest risk for all-cause mortality. Increased mortality was seen with intakes below 50% of group mean. Thus, we observed trends between low energy intake and reduced risk for all-cause mortality in humans until energy intake fell to less than half the group mean, consistent with previous findings in other species.
- Subjects
MORTALITY; DIET; FOOD habits; JAPANESE American men; DEMOGRAPHY
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2004, Vol 59, Issue 8, p789
- ISSN
1079-5006
- Publication type
Article
- DOI
10.1093/gerona/59.8.B789