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- Title
Exploring the Phytochemicals of Acacia melanoxylon R. Br.
- Authors
Alves, Diana; Duarte, Sidónio; Arsénio, Pedro; Gonçalves, Joana; Rodrigues, Cecília M. P.; Lourenço, Ana; Máximo, Patrícia
- Abstract
Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3β-Z-coumaroyl lupeol, 3β-E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3β-E-coumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident.
- Subjects
ACACIA; MASS spectrometry; NUCLEAR magnetic resonance spectroscopy; COLORECTAL cancer; INTRODUCED species
- Publication
Plants (2223-7747), 2021, Vol 10, Issue 12, p2698
- ISSN
2223-7747
- Publication type
Article
- DOI
10.3390/plants10122698