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- Title
Impaired Notch signalling: the unifying mechanism explaining the pathogenesis of hidradenitis suppurativa (acne inversa).
- Authors
Melnik, B.C.; Plewig, G.
- Abstract
The article offers information on the Impaired Notch signalling. It informs that Notch pathway is required for hair follicle terminal differentiation and for postnatal hair cycle homeostasis. It further mentions that notch signalling results in inhibition of the hair growth cycle, conversion of hair follicles into cysts, and inhibition of sebaceous gland differentiation.
- Subjects
NOTCH proteins; EPITHELIUM; BODY fluids; HOMEOSTASIS; TUMORS
- Publication
British Journal of Dermatology, 2013, Vol 168, Issue 4, p876
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/bjd.12068