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- Title
A case of chromoblastomycosis with an unusual clinical manifestation caused byPhialophora verrucosaon an unexposed area: treatment with a combination of amphotericin B and 5-flucytosine.
- Authors
Park, S.-G.; Oh, S.-H.; Suh, S.-B.; Lee, K.-H.; Chung, K.-Y.
- Abstract
Chromoblastomycosis is a cutaneous and subcutaneous mycotic disease caused by the dematiaceous (black) fungi. Five species of fungi are known generally to be the cause:Fonsecaea pedrosoi,Phialophora verrucosa,Cladosporium carrionii,F. compactaandRhinocladiella cerphilum. In infected tissue they can appear as pigmented sclerotic bodies, commonly called‘copper pennies’, which are pathognomonic of chromoblastomycosis. The infection usually occurs through traumatic skin inoculation, with the majority of lesions occurring on the feet and legs of outdoor workers. We report a patient in whom the lesions had begun on the right breast, which is an unexposed area, without a history of trauma. A uniform, reliable treatment does not exist but our patient was mycologically cured with the use of amphotericin B and the subsequent combination of 5-flucytosine and itraconazole.
- Subjects
PHIALOPHORA; AMPHOTERICIN B; POLYENE antibiotics; SKIN diseases; FUNGI; SCLERA
- Publication
British Journal of Dermatology, 2005, Vol 152, Issue 3, p560
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.2005.06424.x