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- Title
Reply to "Hepatocellular carcinoma in thalassemia and other hemoglobinopathies".
- Authors
Origa, Raffaella; Gianesin, Barbara; Longo, Filomena; Di Maggio, Rosario; Cassinerio, Elena; Gamberini, Maria Rita; Pinto, Valeria Maria; Casale, Maddalena; La Nasa, Giorgio; Caocci, Giovanni; Piroddi, Antonio; Piolatto, Andrea; Di Mauro, Alessandra; Romano, Claudia; Gigante, Antonia; Barella, Susanna; Maggio, Aurelio; Graziadei, Giovanna; Perrotta, Silverio; Forni, Gian Luca
- Abstract
Furthermore, cirrhosis was present in 83% of patients with transfusion-dependent thalassemia (45 of 54), in 92% of patients with non-transfusion-dependent thalassemia (12 of 13), and in 75% of patients with sickle cell disease (6 of 8; I p i = .5). Only for 30 of the patients with cirrhosis do we have the date of the diagnosis: 25 of 30 (83%) had a previous diagnosis, and 5 of 30 (17%) had a simultaneous diagnosis. We thank Dr Mancuso and colleagues for their knowledgeable comments about our study.[1] In particular, one point raised is that the study does not address the question of the rates of patients with hepatocellular carcinoma (HCC) with and without concomitant cirrhosis.
- Subjects
HEPATOCELLULAR carcinoma; THALASSEMIA
- Publication
Cancer (0008543X), 2023, Vol 129, Issue 10, p1616
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.34736