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- Title
Comparison of the Prevalence of Antibodies to Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus) in Brazil and Colorado.
- Authors
Zhang, Xing-quan; Fitzpatrick, Lisa; Campbell, Thomas B.; Badaro, Roberto; Schechter, Mauro; de Fatima Melo, Maria; Brites, Carlos; Sampaio, Diana P.; Schooley, Robert T.
- Abstract
The prevalence of human herpesvirus 8 (HHV-8; Kaposi's sarcoma [KS] herpesvirus) infection was determined by IFA in 297 persons living in Brazil and Colorado. The prevalence of antibody to HHV-8 in human immunodeficiency virus (HIV) type 1—seropositive gay men with and without KS was similar in Brazil and Colorado. In Brazil, the prevalence of HHV-8 antibody was significantly greater in HIV-1—seronegative gay men than in HIV-1-seronegative male intravenous drug users. HHV-8—seropositive Brazilian gay men who had a clinical diagnosis of KS or who were infected with HIV-1 had significantly higher titers of HHV-8 antibody than did HHV-8-seropositive, HIV-1—seronegative Brazilian gay men. These findings provide further support for the association between HHV-8 infection and KS and suggest that, as in the United States, HHV-8 infection is transmitted sexually in Brazil.
- Publication
Journal of Infectious Diseases, 1998, Vol 178, Issue 5, p1488
- ISSN
0022-1899
- Publication type
Article