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- Title
Cytokine Concentrations in Sputum of Asthmatic Patients.
- Authors
Konno, Shin-ichi; Gonokami, Yoshiki; Kurokawa, Masatsugu; Kawazu, Kenta; Asano, Kazuhito; Okamoto, Ken-ichi; Adachi, Mitsuru
- Abstract
To examine whether levels of inflammatory cytokines and eosinophil cationic protein (ECP) in the sputum reflect the severity of bronchial asthma, we measured their levels in the sputum of symptomatic and asymptomatic asthmatics. Interleukin (IL)-1β IL-5, IL-6, IL-8, RANTES, tumor necrosis factor-α and ECP concentrations in the sputum of symptomatic patients were significantly higher than in asymptomatic subjects. These findings suggest that these inflammatory cytokines are involved in the exacerbation of asthma. Copyright © 1996 S. Karger AG, Basel
- Publication
International Archives of Allergy & Immunology, 1996, Vol 109, Issue 1, p73
- ISSN
1018-2438
- Publication type
Article
- DOI
10.1159/000237234