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- Title
Advancing the central role of non-model biorepositories in predictive modeling of emerging pathogens.
- Authors
Colella, Jocelyn P.; Cobos, Marlon E.; Salinas, Irene; Cook, Joseph A.
- Abstract
The COVID-19 pandemic demonstrated the insufficiency of a reactive approach to emerging zoonotic pathogens. Integrating new computational tools with biorepository archives can be powerfully used to (1) identify new pathogens with zoonotic potential, (2) understand key interactions among pathogens and their wild hosts, and (3) model host-pathogen interactions and risk landscapes in geographic, genomic, and environmental space. Non-model host-pathogen interactions, ecology, and immunology A pathogen can only cause disease when it encounters a susceptible host in an environment conducive to infection.
- Subjects
LIFE sciences; PREDICTION models; FEVER
- Publication
PLoS Pathogens, 2023, Vol 18, Issue 6, p1
- ISSN
1553-7366
- Publication type
Article
- DOI
10.1371/journal.ppat.1011410