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- Title
Being pregnant in the COVID‐19 pandemic: Effects on the placenta in all aspects.
- Authors
Seymen, C. Merve
- Abstract
The coronavirus disease 2019 (COVID‐19), which had spread to the world from Wuhan (China) in late December, was announced as a pandemic by the World Health Organization in March 2020. In addition to acute respiratory syndrome symptoms, this virus also affects nonrespiratory organs, according to existing data. ACE2 and TMPRSS2, which play a critical role in the entrance of SARS‐COV‐2 into the cell, are coexpressed in placental development stages, so the placenta also carries a risk for this virus. Many studies have shown that this virus causes some histopathological changes in the placenta. The vertical transmission of the virus is not yet clear, but available data have shown that the indirect effects of the virus can be seen on the fetus. This article focuses on revealing the effects of the virus on the placenta in all aspects. Highlights: •The placenta also shows antiviral activity due to placental growth factors, cytokines, and chemokines, so the use of placental extracts as therapeutic agents in the treatment of COVID‐19 needs authority regulations and clinical guidelines.
- Subjects
WUHAN (China); COVID-19 pandemic; WORLD Health Organization; COVID-19; PLACENTAL growth factor; COVID-19 treatment; PLACENTA
- Publication
Journal of Medical Virology, 2021, Vol 93, Issue 5, p2769
- ISSN
0146-6615
- Publication type
Article
- DOI
10.1002/jmv.26857