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- Title
Glucose-containing imidazolium salt-catalyzed cross-aldol reaction of isatins and unactivated ketones.
- Authors
Wan, Yu; Yuan, Rui; Cui, Hao; Zhang, Xiao-xiao; Li, Ming-qi; Xu, Jiang-biao; Dou, Peng-fei; Zhang, Long-yan; Wu, Hui
- Abstract
Ketone-ketone cross-aldol reaction of isatins and unactivated ketones was catalyzed by glucose-containing imidazolium salt β-1-imidazole-2,3,4,6-tetra-o-hydroxy-d-glucopyranosyl bromide in neutral condition to generate 3-alkyl-3-hydroxyindolin-2-ones in excellent yield.
- Subjects
IMIDAZOLES; ISATIN; KETONES; CATALYSIS; ALDOLS
- Publication
Research on Chemical Intermediates, 2018, Vol 44, Issue 4, p2561
- ISSN
0922-6168
- Publication type
Article
- DOI
10.1007/s11164-017-3246-3