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- Title
Solvent-free efficient one-pot synthesis of Biginelli and Hantzsch compounds catalyzed by potassium phthalimide as a green and reusable organocatalyst.
- Authors
Kiyani, Hamzeh; Ghiasi, Maryam
- Abstract
The usage of potassium phthalimide (PPI) for the simple and green one-step multicomponent synthesis of Hantzsch 1,4-dihydropyridines, polyhydroquinolines, 3,4-dihydropyrimidin-2(1 H)-ones/thiones, and octahydroquinazolinones under solventless conditions at 120 °C is reported. The method is operationally simple, environmentally benign, and has relatively high yields. The other merits of this method include efficient, clean, green, and catalyst reusability.
- Subjects
POTASSIUM compounds; SOLVENTS; PHTHALIMIDES; ORGANOCATALYSIS; ORGANIC synthesis
- Publication
Research on Chemical Intermediates, 2015, Vol 41, Issue 8, p5177
- ISSN
0922-6168
- Publication type
Article
- DOI
10.1007/s11164-014-1621-x