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- Title
Biomarkers for the noninvasive diagnosis of endometriosis.
- Authors
Hubencu, Cristina; Şandru, Florica; Petca, Răzvan-Cosmin; Dumitraşcu, Mihai-Cristian; Mehedințu, Claudia; Petca, Aida
- Abstract
Endometriosis is a hormone-dependent disorder that affects the female reproductive system. It is defined by the growth of endometrial- like tissue outside the uterus. The disease can be found in various anatomical areas such as the peritoneum wall, ovaries, rectosigmoid colon and bladder, and in some cases, in distant organs like the lung, liver and brain. The symptoms include pelvic pain, painful menstrual cramps, dyspareunia and infertility. The disease's precise causes and risk factors are not fully understood, but factors such as genetics, exposure to endocrine-disrupting chemicals and certain lifestyle factors may play a role. The diagnostic process for endometriosis can be challenging, and at the moment, laparoscopic surgery is the gold standard for confirmation. However, extensive research has been conducted to find noninvasive diagnostic biomarkers for the disease. Several candidate biomarkers have shown promise, but further research is needed to validate their effectiveness and specificity.
- Subjects
NONINVASIVE diagnostic tests; ENDOMETRIOSIS; PELVIC pain; BIOMARKERS; GENITALIA; PIGMENT epithelium-derived factor
- Publication
Obstetrică şi Ginecologie, 2024, Vol 72, Issue 1, p10
- ISSN
1220-5532
- Publication type
Article