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- Title
An unusual case of glomerulonephritis in a patient with non-Hodgkin Mucosal Associated Lymphoid Tissue (MALT) B-cell lymphoma.
- Authors
See Cheng Yeo; Khoon Leong Chuah; Hwei Yee Lee; Liew, Adrian
- Abstract
Background: Kidney involvement in non-Hodgkin lymphoma is well recognized and glomerulonephritis, when present, has been commonly reported to be associated with a membranoproliferative pattern. Case presentation: We report a case of a 58-year-old lady with a recurrence of non-Hodgkin MALT B-cell lymphoma, presenting with acute kidney injury, nephrotic range proteinuria and a cellular urinalysis. She underwent a renal biopsy that showed a severe diffuse proliferative and exudative lupus-like glomerulonephritis, which is likely paraneoplastic in nature. We discuss the differential diagnosis and possible pathogenesis of glomerular injury in lymphoma-related proliferative glomerulonephritis. Conclusion: Differentiating between true lupus nephritis and a paraneoplastic glomerulonephritis is important, as it would have significant implications on treatment and clinical course.
- Subjects
HODGKIN'S disease; B cells; ACUTE kidney failure; PROTEINURIA; URINALYSIS; RENAL biopsy; DIAGNOSIS; PATIENTS; DISEASES
- Publication
BMC Nephrology, 2013, Vol 14, Issue 1, p1
- ISSN
1471-2369
- Publication type
Case Study
- DOI
10.1186/1471-2369-14-158