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- Title
RSV vaccine: Beating the virus at its own game.
- Authors
Moscona, Anne
- Abstract
The article discusses a study published in the issue, focusing on the use of respiratory syncytial virus (RSV) to develop an innovative live attenuated vaccine. Topics discussed include the role of immune-mediated injury in preventing the development of an RSV vaccine; the need for adequate levels of neutralizing antibody and CD8+ virus-specific cytotoxic T lymphocytes (CTLs) in a vaccine; and the gene deletion used in the study.
- Subjects
RESPIRATORY syncytial virus infection vaccines; IMMUNE system; IMMUNOGLOBULINS; CYTOTOXIC T cells; DELETION mutation
- Publication
Science Translational Medicine, 2015, Vol 7, Issue 312, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aad2515