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- Title
The Predictive Value of Monocyte Count to High-Density Lipoprotein Cholesterol Ratio in Restenosis After Drug-Eluting Stent Implantation.
- Authors
Nan, Jing; Meng, Shuai; Hu, Hongyu; Jia, Ruofei; Chen, Ce; Peng, Jianjun; Jin, Zening
- Abstract
Background: The clinical value of monocyte count to high-density lipoprotein cholesterol ratio (MHR) in in-stent restenosis (ISR) of patients who have undergone bare metal stent implantation has been studied. However, the predictive value of MHR in ISR for patients who have undergone drug-eluting stent (DES) implantation has not been explored. Methods: Non-ST segment elevation acute coronary syndrome (NSTE-ACS) patients who had undergone DES implantation and coronary angiography follow-up at the Beijing Shijitan Hospital, Capital Medical University, between January 1, 2008, and December 31, 2018, were retrospectively enrolled. Patients were divided into ISR and non-ISR groups depending on the follow-up coronary angiography results. Relative clinical information was recorded and analyzed. The receiver operating characteristic curve analysis was used to determine the optimum cut-off pre-procedural MHR to predict ISR. Results: A total of 214 patients were enrolled in our study. The mean period between two coronary angiography procedures was 25.4± 9.8 months. Percutaneous coronary intervention due to NSTE myocardial infarction, a bifurcation lesion, increased platelet count, and a high MHR were the independent risk factors in multivariate logistic regression analyses. Conclusion: Our results indicated that elevated MHR is an independent and useful predictor of ISR in NSTE-ACS patients who have undergone DES implantation.
- Subjects
HIGH density lipoproteins; DRUG-eluting stents; PLATELET count; RECEIVER operating characteristic curves; MYOCARDIAL infarction; CORONARY angiography; PERCUTANEOUS coronary intervention
- Publication
International Journal of General Medicine, 2020, Vol 13, p1255
- ISSN
1178-7074
- Publication type
Article
- DOI
10.2147/IJGM.S275202