We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Modulation of the immune response with T-cell epitopes: the ultimate goal for specific immunotherapy of autoimmune disease.
- Authors
Fairchild, P. J.; Thorpe, C. J.; Travers, P. J.; Wraith, D. C.
- Abstract
Focuses on the modulation of immune response with T-cell epitopes for immunotherapy of autoimmune disease. Significance of the encounter by antigen-specific T-cell receptor of complexes between peptides and major histocompatibility complex (MHC) in T-cell activation; Examination of the interaction between the dominant autoantigenic epitope of mice with experimental autoimmune encephalomyelitis (EAE) and its class II MHC; Investigation of the viability of MHC blockade as a treatment for EAE.
- Subjects
IMMUNOREGULATION; T cells; EPITOPES; AUTOIMMUNE diseases; IMMUNOTHERAPY; IMMUNOLOGY
- Publication
Immunology, 1994, Vol 81, Issue 4, p487
- ISSN
0019-2805
- Publication type
Article