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- Title
Glomerular Filtration Rate is Associated With Burden of Coronary Atherosclerosis in Patients With Acute Coronary Syndrome.
- Authors
Duran, Mustafa; Uysal, Onur Kadir; Gunebakmaz, Ozgur; Baran, Oguzhan; Turfan, Murat; Ornek, Ender; Cetin, Mustafa; Murat, Sani Namik; Yarlioglues, Mikail; Karadeniz, Muhammed; Kurtul, Alpaslan; Kaya, Mehmet Gungor
- Abstract
We aimed to elucidate the relationship between mild to moderate renal impairements and burden of atherosclerosis in patients with acute coronary syndrome (ACS). A total of 380 patients with ACS were included in the study. Gensini and SYNTAX scores were also calculated. Kidney function was classified based on estimated glomerular filtration rate (eGFR) into stage 1: eGFR >90, stage 2: 60 to 89, and stage 3: 30 to 60 mL/min per 1.73 m2. Gensini and SYNTAX scores were higher in stages 2 and 3 than in stage 1. Also, the number of diseased vessels, number of critical lesions (>50 and 70%), left main disease, and number of total occlusion vessels were higher in stages 2 and 3 than in stage 1. Multivariate linear regression analysis demonstrated that a decreased eGFR was an independent risk factor for SYNTAX and Gensini scores together with age and male gender.
- Subjects
ANGIOGRAPHY; ANALYSIS of variance; CHI-squared test; CONFIDENCE intervals; CORONARY disease; STATISTICAL correlation; EPIDEMIOLOGY; GLOMERULAR filtration rate; KIDNEY diseases; REGRESSION analysis; RISK assessment; STATISTICS; T-test (Statistics); U-statistics; LOGISTIC regression analysis; DATA analysis; DATA analysis software; ACUTE coronary syndrome; DESCRIPTIVE statistics; DISEASE complications
- Publication
Angiology, 2014, Vol 65, Issue 4, p350
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/0003319713486536