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- Title
Arterial Ultrasound Screening as a Tool for Coronary Risk Assessment in Asymptomatic Men and Women.
- Authors
Cournot, Maxime; Bura, Alessandra; Cambou, Jean-Pierre; Taraszkiewicz, Dorota; Maloizel, Julie; Galinier, Michel; Broutin, Hélène Hanaire; Chamontin, Bernard; Carrié, Didier; Ferrieres, Jean
- Abstract
One of the imaging tests most commonly used to assess cardiovascular diseases (CVDs) in daily practice is Doppler ultrasonography of the carotid and femoral arteries. We included 2709 participants with no history or symptoms of CVD; they had a risk factor assessment and a carotid and femoral ultrasonography at baseline. Incident cases of definite coronary events were recorded during a median follow-up of 6 years. Approximately, 63% of the sample presented abnormalities (carotid stenosis >50%, carotid plaque, femoral plaque, increased intima–media thickness [IMT]). A moderately increased IMT (>0.63 mm) or the presence of carotid or femoral artery plaque was related to prognosis. The associations persisted after adjustment for pretest risk, treatment with statins, and other Doppler ultrasonography abnormalities. The hazard ratio increased significantly with the number of abnormalities (varying from 2.35 [1.16-4.74] to 14.83 [6.47-33.9]).
- Subjects
FRANCE; ACADEMIC medical centers; DOPPLER ultrasonography; ANALYSIS of variance; CARDIOVASCULAR disease diagnosis; CARDIOVASCULAR diseases risk factors; CHI-squared test; CORONARY arteries; LONGITUDINAL method; MULTIVARIATE analysis; QUESTIONNAIRES; RESEARCH funding; RISK assessment; STATISTICS; PROPORTIONAL hazards models; DATA analysis software; KAPLAN-Meier estimator
- Publication
Angiology, 2012, Vol 63, Issue 6, p282
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/0003319711414865