We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Surveillance for Adenoviruses in Bats in Italy.
- Authors
Diakoudi, Georgia; Lanave, Gianvito; Moreno, Ana; Chiapponi, Chiara; Sozzi, Enrica; Prosperi, Alice; Larocca, Vittorio; Losurdo, Michele; Decaro, Nicola; Martella, Vito; Lavazza, Antonio; Lelli, Davide
- Abstract
Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a Pipistrellus kuhlii, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the Pipistrellus pipistrellus strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts.
- Subjects
ITALY; GERMANY; BATS; DNA polymerases; GENETIC epidemiology; ADENOVIRUSES; CELL lines; NUCLEOTIDE sequencing
- Publication
Viruses (1999-4915), 2019, Vol 11, Issue 6, p523
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v11060523