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Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass.
Published in:
Diabetologia, 2009, v. 52, n. 6, p. 1122, doi. 10.1007/s00125-009-1317-8
By:
- Delghingaro-Augusto, V.;
- Nolan, C.;
- Gupta, D.;
- Jetton, T.;
- Latour, M.;
- Peshavaria, M.;
- Madiraju, S.;
- Joly, É.;
- Peyot, M.-L.;
- Prentki, M.;
- Leahy, J.
Publication type:
Article
Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial.
Published in:
Diabetologia, 2009, v. 52, n. 4, p. 723, doi. 10.1007/s00125-008-1256-9
By:
- Coletta, D.;
- Sriwijitkamol, A.;
- Wajcberg, E.;
- Tantiwong, P.;
- Li, M.;
- Prentki, M.;
- Madiraju, M.;
- Jenkinson, C.;
- Cersosimo, E.;
- Musi, N.;
- DeFronzo, R.
Publication type:
Article
Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.
Published in:
Diabetologia, 2006, v. 49, n. 9, p. 2120, doi. 10.1007/s00125-006-0305-5
By:
- Nolan, C. J.;
- Leahy, J. L.;
- Delghingaro-Augusto, V.;
- Moibi, J.;
- Soni, K.;
- Peyot, M.-L.;
- Fortier, M.;
- Guay, C.;
- Lamontagne, J.;
- Barbeau, A.;
- Przybytkowski, E.;
- Joly, E.;
- Masiello, P.;
- Wang, S.;
- Mitchell, G. A.;
- Prentki, M.
Publication type:
Article
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity Glucagon-like peptide-1 prevents gluco- and lipotoxicity.
Published in:
Diabetologia, 2004, v. 47, n. 5, p. 806, doi. 10.1007/s00125-004-1379-6
By:
- Buteau, J.;
- El-Assaad, W.;
- Rhodes, C. J.;
- Rosenberg, L.;
- Joly, E.;
- Prentki, M.
Publication type:
Article
PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Published in:
2012
By:
- Iglesias J;
- Barg S;
- Vallois D;
- Lahiri S;
- Roger C;
- Yessoufou A;
- Pradevand S;
- McDonald A;
- Bonal C;
- Reimann F;
- Gribble F;
- Debril MB;
- Metzger D;
- Chambon P;
- Herrera P;
- Rutter GA;
- Prentki M;
- Thorens B;
- Wahli W;
- Iglesias, José
Publication type:
journal article
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity.
Published in:
2012
By:
- Jacovetti C;
- Abderrahmani A;
- Parnaud G;
- Jonas JC;
- Peyot ML;
- Cornu M;
- Laybutt R;
- Meugnier E;
- Rome S;
- Thorens B;
- Prentki M;
- Bosco D;
- Regazzi R;
- Jacovetti, Cécile;
- Abderrahmani, Amar;
- Parnaud, Géraldine;
- Jonas, Jean-Christophe;
- Peyot, Marie-Line;
- Cornu, Marion;
- Laybutt, Ross
Publication type:
journal article
Lysophosphatidic acid impairs glucose homeostasis and inhibits insulin secretion in high-fat diet obese mice.
Published in:
Diabetologia, 2013, v. 56, n. 6, p. 1394, doi. 10.1007/s00125-013-2891-3
By:
- Rancoule, C.;
- Attané, C.;
- Grès, S.;
- Fournel, A.;
- Dusaulcy, R.;
- Bertrand, C.;
- Vinel, C.;
- Tréguer, K.;
- Prentki, M.;
- Valet, P.;
- Saulnier-Blache, J.
Publication type:
Article
G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.
Published in:
Diabetologia, 2012, v. 55, n. 10, p. 2682, doi. 10.1007/s00125-012-2650-x
By:
- Ferdaoussi, M.;
- Bergeron, V.;
- Zarrouki, B.;
- Kolic, J.;
- Cantley, J.;
- Fielitz, J.;
- Olson, E.;
- Prentki, M.;
- Biden, T.;
- MacDonald, P.;
- Poitout, V.
Publication type:
Article
Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass.
Published in:
Diabetologia, 2010, v. 53, n. 11, p. 2369, doi. 10.1007/s00125-010-1850-5
By:
- Fontés, G.;
- Zarrouki, B.;
- Hagman, D.;
- Latour, M.;
- Semache, M.;
- Roskens, V.;
- Moore, P.;
- Prentki, M.;
- Rhodes, C.;
- Jetton, T.;
- Poitout, V.
Publication type:
Article
Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats.
Published in:
2007
By:
- Lamontagne J;
- Masiello P;
- Marcil M;
- Delghingaro-Augusto V;
- Burelle Y;
- Prentki M;
- Nolan CJ
Publication type:
Journal Article
Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.
Published in:
2008
By:
- Dallaire P;
- Bellmann K;
- Laplante M;
- Gélinas S;
- Centeno-Baez C;
- Penfornis P;
- Peyot M;
- Latour MG;
- Lamontagne J;
- Trujillo ME;
- Scherer PE;
- Prentki M;
- Deshaies Y;
- Marette A;
- Dallaire, Patrice;
- Bellmann, Kerstin;
- Laplante, Mathieu;
- Gélinas, Stéphanie;
- Centeno-Baez, Carolina;
- Penfornis, Patrice
Publication type:
journal article
Fatty acid signaling in the beta-cell and insulin secretion.
Published in:
2006
By:
- Nolan CJ;
- Madiraju MSR;
- Delghingaro-Augusto V;
- Peyot M;
- Prentki M;
- Nolan, Christopher J;
- Madiraju, Murthy S R;
- Delghingaro-Augusto, Viviane;
- Peyot, Marie-Line;
- Prentki, Marc
Publication type:
journal article
Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.
Published in:
2001
By:
- Buteau, Jean;
- Foisy, Sylvain;
- Rhodes, Christopher J.;
- Carpenter, Lee;
- Biden, Trevor J.;
- Prentki, Marc;
- Buteau, J;
- Foisy, S;
- Rhodes, C J;
- Carpenter, L;
- Biden, T J;
- Prentki, M
Publication type:
journal article
A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.
Published in:
2001
By:
- Roduit, Raphael;
- Masiello, Pellegrino;
- Shu Pei Wang;
- Hong Li;
- Mitchell, Grant A.;
- Prentki, Marc;
- Roduit, R;
- Masiello, P;
- Wang, S P;
- Li, H;
- Mitchell, G A;
- Prentki, M
Publication type:
journal article
Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?
Published in:
2001
By:
- Lameloise, Nathalie;
- Muzzin, Patrick;
- Prentki, Marc;
- Assimacopoulos-Jeannet, Francoise;
- Lameloise, N;
- Muzzin, P;
- Prentki, M;
- Assimacopoulos-Jeannet, F
Publication type:
journal article
Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.
Published in:
2000
By:
- Dillon, J S;
- Yaney, G C;
- Zhou, Y;
- Voilley, N;
- Bowen, S;
- Chipkin, S;
- Bliss, C R;
- Schultz, V;
- Schuit, F C;
- Prentki, M;
- Waxman, D J;
- Corkey, B E
Publication type:
journal article
Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion.
Published in:
2000
By:
- Farfari, Salah;
- Schulz, Vera;
- Corkey, Barbara;
- Prentki, Marc;
- Farfari, S;
- Schulz, V;
- Corkey, B;
- Prentki, M
Publication type:
journal article
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.
Published in:
2000
By:
- Hohmeier, Hans E.;
- Mulder, Hindrik;
- Chen, Guoxun;
- Henkel-Rieger, Rosemarie;
- Prentki, Marc;
- Newgard, Christopher B.;
- Hohmeier, H E;
- Mulder, H;
- Chen, G;
- Henkel-Rieger, R;
- Prentki, M;
- Newgard, C B
Publication type:
journal article
Palmitate and oleate induce the immediate-early response genes c-fos and nur-77 in the pancreatic beta-cell line INS-1.
Published in:
1999
By:
- Roche, Enrique;
- Buteau, Jean;
- Aniento, Inmaculada;
- Reig, Juan Antonio;
- Soria, Bernat;
- Prentki, Marc;
- Roche, E;
- Buteau, J;
- Aniento, I;
- Reig, J A;
- Soria, B;
- Prentki, M
Publication type:
journal article
Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression.
Published in:
1998
By:
- Roche, Enrique;
- Farfari, Salah;
- Witters, Lee A.;
- Assimacopoulos-Jeannet, Francoise;
- Thumelin, Stephane;
- Brun, Thierry;
- Corkey, Barbara E.;
- Saha, Asish K.;
- Prentki, Marc;
- Roche, E;
- Farfari, S;
- Witters, L A;
- Assimacopoulos-Jeannet, F;
- Thumelin, S;
- Brun, T;
- Corkey, B E;
- Saha, A K;
- Prentki, M
Publication type:
journal article
Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.
Published in:
1997
By:
- Brun, Thierry;
- Assimacopoulos-Jeannet, Françoise;
- Corkey, Barbara E.;
- Prentki, Marc;
- Brun, T;
- Assimacopoulos-Jeannet, F;
- Corkey, B E;
- Prentki, M
Publication type:
journal article
Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.
Published in:
1996
By:
- Brun, Thierry;
- Roche, Enrique;
- Assimacopoulos-Jeannet, Francoise;
- Corkey, Barbara E.;
- Kim, Ki-Han;
- Prentki, Marc;
- Brun, T;
- Roche, E;
- Assimacopoulos-Jeannet, F;
- Corkey, B E;
- Kim, K H;
- Prentki, M
Publication type:
journal article
Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass.
Published in:
2010
By:
- Peyot ML;
- Pepin E;
- Lamontagne J;
- Latour MG;
- Zarrouki B;
- Lussier R;
- Pineda M;
- Jetton TL;
- Madiraju SR;
- Joly E;
- Prentki M;
- Peyot, Marie-Line;
- Pepin, Emilie;
- Lamontagne, Julien;
- Latour, Martin G;
- Zarrouki, Bader;
- Lussier, Roxane;
- Pineda, Marco;
- Jetton, Thomas L;
- Madiraju, S R Murthy
Publication type:
journal article

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